Translating Frailty Research Into Clinical Practice: Insights From the Successful Aging and Frailty Evaluation Clinic

被引:17
作者
Huisingh-Scheetz, Megan [1 ]
Martinchek, Michelle [1 ]
Becker, Yolanda [2 ]
Ferguson, Mark K. [3 ]
Thompson, Katherine [1 ]
机构
[1] Univ Chicago Med, Dept Med, Sect Geriatr & Palliat Med, Chicago, IL USA
[2] Univ Chicago Med, Dept Surg, Sect Transplant Surg, Chicago, IL USA
[3] Univ Chicago Med, Dept Surg, Thorac Surg Sect, Chicago, IL USA
关键词
Frailty; clinical practice; aging; consultation; OLDER-ADULTS; ELDERLY-PATIENTS; THERAPEUTIC INTERVENTIONS; INSTRUMENTAL ACTIVITIES; FUNCTIONAL DECLINE; ASSOCIATION; MORTALITY; IMPACT; CONSENSUS; OUTCOMES;
D O I
10.1016/j.jamda.2018.12.002
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Aging researchers have been studying frailty for decades. Experts agree that frailty is a medical syndrome marked by reduced physiologic function, which increases the risk of vulnerability and short-term mortality, particularly in the face of a stressor. Frailty has been shown to predict poor outcomes including falls, disability, major morbidity following surgery, and mortality among older adults. Despite hundreds of papers identifying frailty as a useful marker of risk, its translation into clinical practice has lagged. The Successful Aging and Frailty Evaluation (SAFE) clinic was established in 2011 specifically to implement routine and structured frailty assessment and management in a variety of referred patients. Now, more than 7 years after its inception, we offer our "in the trenches" clinical perspective on logistical challenges, the clinical utility of the frailty assessment, and future frailty needs and targets to help further the frailty translation research efforts. (C) 2018 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
引用
收藏
页码:672 / 678
页数:7
相关论文
共 51 条
  • [1] Frailty in Older Adults: A Nationally Representative Profile in the United States
    Bandeen-Roche, Karen
    Seplaki, Christopher L.
    Huang, Jin
    Buta, Brian
    Kalyani, Rita R.
    Varadhan, Ravi
    Xue, Qian-Li
    Walston, Jeremy D.
    Kasper, Judith D.
    [J]. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2015, 70 (11): : 1427 - 1434
  • [2] Aging as a Biological Target for Prevention and Therapy
    Barzilai, Nir
    Cuervo, Ana Maria
    Austad, Steve
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2018, 320 (13): : 1321 - 1322
  • [3] Screening for Frailty in Thoracic Surgical Patients
    Beckert, Angela K.
    Huisingh-Scheetz, Megan
    Thompson, Katherine
    Celauro, Amy D.
    Williams, Jordan
    Pachwicewicz, Paul
    Ferguson, Mark K.
    [J]. ANNALS OF THORACIC SURGERY, 2017, 103 (03) : 956 - 961
  • [4] Therapeutic Interventions for Frail Elderly Patients: Part II. Ongoing and Unpublished Randomized Trials
    Bendayan, Melissa
    Bibas, Lior
    Levi, Michael
    Mullie, Louie
    Forman, Daniel E.
    Afilalo, Jonathan
    [J]. PROGRESS IN CARDIOVASCULAR DISEASES, 2014, 57 (02) : 144 - 151
  • [5] Bergman H, 2017, JHU NIA FRAILT SCI M
  • [6] Effect of Protein Intake on Lean Body Mass in Functionally Limited Older Men A Randomized Clinical Trial
    Bhasin, Shalender
    Apovian, Caroline M.
    Travison, Thomas G.
    Pencina, Karol
    Moore, Lynn L.
    Huang, Grace
    Campbell, Wayne W.
    Li, Zhuoying
    Howland, Andrew S.
    Chen, Ruo
    Knapp, Philip E.
    Singer, Martha R.
    Shah, Mitali
    Secinaro, Kristina
    Eder, Richard V.
    Hally, Kathleen
    Schram, Haley
    Bearup, Richelle
    Beleva, Yusnie M.
    McCarthy, Ashley C.
    Woodbury, Erin
    McKinnon, Jennifer
    Fleck, Geeta
    Storer, Thomas W.
    Basaria, Shehzad
    [J]. JAMA INTERNAL MEDICINE, 2018, 178 (04) : 530 - 541
  • [7] Therapeutic Interventions for Frail Elderly Patients: Part I. Published Randomized Trials
    Bibas, Lior
    Levi, Michael
    Bendayan, Melissa
    Mullie, Louis
    Forman, Daniel E.
    Afilalo, Jonathan
    [J]. PROGRESS IN CARDIOVASCULAR DISEASES, 2014, 57 (02) : 134 - 143
  • [8] Frailty assessment instruments: Systematic characterization of the uses and contexts of highly-cited instruments
    Buta, Brian J.
    Walston, Jeremy D.
    Godino, Job G.
    Park, Minsun
    Kalyani, Rita R.
    Xue, Qian-Li
    Bandeen-Roche, Karen
    Varadhan, Ravi
    [J]. AGEING RESEARCH REVIEWS, 2016, 26 : 53 - 61
  • [9] A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial
    Cameron, Ian D.
    Fairhall, Nicola
    Langron, Colleen
    Lockwood, Keri
    Monaghan, Noeline
    Aggar, Christina
    Sherrington, Catherine
    Lord, Stephen R.
    Kurrle, Susan E.
    [J]. BMC MEDICINE, 2013, 11
  • [10] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases
    Cardoso, Ana Luisa
    Fernandes, Adelaide
    Aguilar-Pimentel, Juan Antonio
    de Angelis, Martin Hrabe
    Guedes, Joana Ribeiro
    Brito, Maria Alexandra
    Ortolano, Saida
    Pani, Giovambattista
    Athanasopoulou, Sophia
    Gonos, Efstathios S.
    Schosserer, Markus
    Grillari, Johannes
    Peterson, Part
    Tuna, Bilge Guvenc
    Dogan, Soner
    Meyer, Angelika
    van Os, Ronald
    Trendelenburg, Anne-Ulrike
    [J]. AGEING RESEARCH REVIEWS, 2018, 47 : 214 - 277