THE MAIN FUNCTION OF HIS175, TRP179, AND TYR190 RESIDUES OF THE OBELIN BINDING SITE IS TO STABILIZE THE HYDROPEROXYCOELENTERAZINE INTERMEDIATE

被引：3

作者：

Eremeeva, E. V. ^{[1
]}

Markova, S. V. ^{[1
]}

Frank, L. A. ^{[1
]}

Vysotski, E. S. ^{[1
]}

机构：

[1] Inst Biophys SB RAS, Photobiol Lab, Inst Biophys, Krasnoyarsk 660036, Russia

来源：

BIOLUMINESCENCE AND CHEMILUMINESCENCE: CHEMISTRY, BIOLOGY AND APPLICATIONS | 2007年

关键词：

D O I：

10.1142/9789812770196_0002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：7 / 10

页数：4

共 7 条

[1]

Illarionov BA, 2000, METHOD ENZYMOL, V305, P223

[2] Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine [J].

Liu, ZJ ;

Vysotski, ES ;

Deng, L ;

Lee, J ;

Rose, J ;

Wang, BC .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 311 (02) :433-439

[3] Structure of the Ca2+-regulated photoprotein obelin at 1.7 Å resolution determined directly from its sulfur substructure [J].

Liu, ZJ ;

Vysotski, ES ;

Chen, CJ ;

Rose, JP ;

Lee, J ;

Wang, BC .

PROTEIN SCIENCE, 2000, 9 (11) :2085-2093

[4] BIOLUMINESCENCE OF THE CA2+-BINDING PHOTOPROTEIN, AEQUORIN, AFTER HISTIDINE MODIFICATION [J].

OHMIYA, Y ;

TSUJI, FI .

FEBS LETTERS, 1993, 320 (03) :267-270

[5]

Stanley, 2001, BIOLUMINESCENCE CHEM, P115

[6] Ca2+-regulated photoproteins:: Structural insight into the bioluminescence mechanism [J].

Vysotski, ES ;

Lee, J .

ACCOUNTS OF CHEMICAL RESEARCH, 2004, 37 (06) :405-415

[7] Preparation and preliminary study of crystals of the recombinant calcium-regulated photoprotein obelin from the bioluminescent hydroid Obelia longissima [J].

Vysotski, ES ;

Liu, ZJ ;

Rose, J ;

Wang, BC ;

Lee, J .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1999, 55 :1965-1966

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