Solid form and solubility

被引：20
作者：
Hunter, Christopher A. [1 ]
Prohens, Rafel [2 ,3 ]
机构：
[1] Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England
[2] Univ Barcelona, Unitat Polimorfisme & Calorimetria, Ctr Cient, Baldiri Reixac 10, E-08028 Barcelona, Spain
[3] Univ Barcelona, Unitat Polimorfisme & Calorimetria, Ctr Tecnol, Baldiri Reixac 10, E-08028 Barcelona, Spain
来源：
CRYSTENGCOMM | 2017年 / 19卷 / 01期
关键词：
DRUGS; BIOAVAILABILITY; ADVANTAGE;
D O I：
10.1039/c6ce02094a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Factors that determine the solubility of polymorphs and cocrystals are analysed using experimental data to show that the change in the solubility of a compound produced by the formation of a multicomponent crystal can be estimated in a straightforward manner, if the solubilities of the pure compound and the coformer are known.
引用
收藏
页码：23 / 26
页数：4
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