Medullary thymic epithelial cell depletion by conditional deletion of TRAF6 leads to the development of autoimmune hepatitis

被引:0
|
作者
Alexandropoulos, K. [1 ]
Bonito, A. J. [1 ]
Aloman, C. [1 ]
机构
[1] Mt Sinai Sch Med, New York, NY USA
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:116 / 116
页数:1
相关论文
共 50 条
  • [1] CONDITIONAL DELETION OF TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTOR 6 (TRAF6) IN MEDULLARY THYMIC EPITHELIAL CELLS LEADS TO THE DEVELOPMENT OF CLASSICAL AUTOIMMUNE HEPATITIS IN MICE
    Bonito, Anthony J.
    Aloman, Costica
    Fiel, M. Isabel
    Alexandropoulos, Konstantina
    HEPATOLOGY, 2011, 54 : 428A - 428A
  • [2] Conditional deletion of tumor necrosis factor receptor-associated factor 6 (TRAF6) in medullary thymic epithelial cells leads to the development of classical autoimmune hepatitis in mice
    Bonito, Anthony
    Aloman, Costica
    Fiel, Maria
    Danzl, Nichole
    Alexandropoulos, Konstantina
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [3] Medullary thymic epithelial cell depletion leads to autoimmune hepatitis
    Bonito, Anthony J.
    Aloman, Costica
    Fiel, M. Isabel
    Danzl, Nichole M.
    Cha, Sungwon
    Weinstein, Erica G.
    Jeong, Seihwan
    Choi, Yongwon
    Walsh, Matthew C.
    Alexandropoulos, Konstantina
    JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (08): : 3510 - 3524
  • [4] Thymic development - TRAF6 distributes tolerance
    Honey, K
    NATURE REVIEWS IMMUNOLOGY, 2005, 5 (04) : 269 - 269
  • [5] Identification of Novel Thymic Epithelial Cell Subsets Whose Differentiation Is Regulated by RANKL and Traf6
    Danzl, Nichole M.
    Jeong, Seihwan
    Choi, Yongwon
    Alexandropoulos, Konstantina
    PLOS ONE, 2014, 9 (01):
  • [6] TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development
    Jenkinson, S. Rhiannon
    Williams, Joy A.
    Jeon, Hyein
    Zhang, Jingjing
    Nitta, Takeshi
    Ohigashi, Izumi
    Kruhlak, Michael
    Zuklys, Saulius
    Sharrow, Susan
    Adams, Anthony
    Granger, Larry
    Choi, Yongwon
    Siebenlist, Ulrich
    Bishop, Gail A.
    Hollander, Georg A.
    Takahama, Yousuke
    Hodes, Richard J.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (52) : 21107 - 21112
  • [7] Targeted deletion of c-Met in thymic epithelial cells leads to an autoimmune phenotype
    Su, Min
    Hu, Rong
    Song, Yinhong
    Liu, Yalan
    Lai, Laijun
    IMMUNOLOGY AND CELL BIOLOGY, 2018, 96 (02): : 229 - 235
  • [8] TRAF6 is a critical factor for dendritic cell maturation and development
    Kobayashi, T
    Walsh, PT
    Walsh, MC
    Speirs, KM
    Chiffoleau, E
    King, CG
    Hancock, WW
    Caamano, JH
    Hunter, CA
    Scott, P
    Turka, LA
    Choi, YW
    IMMUNITY, 2003, 19 (03) : 353 - 363
  • [9] Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration
    Khusbu, Farjana Yeasmin
    Zhou, Xi
    Roy, Mridul
    Chen, Fang-Zhi
    Cao, Qian
    Chen, Han-Chun
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2020, 118
  • [10] Thymocyte requirements for normal thymic medullary epithelial cell development
    Williams, Joy
    Jeon, Hyein
    Hodes, Richard
    JOURNAL OF IMMUNOLOGY, 2015, 194