Heterotopic Ossification in Orthopaedic Trauma

被引：108

作者：

Nauth, Aaron ^{[1
]}

Giles, Erica ^{[1
]}

Potter, Benjamin K. ^{[2
]}

Nesti, Leon J. ^{[2
]}

O'Brien, Frederick P. ^{[2
]}

Bosse, Michael J. ^{[3
]}

Anglen, Jeffrey O. ^{[4
]}

Mehta, Samir ^{[5
]}

Ahn, Jaimo ^{[5
]}

Miclau, Theodore ^{[6
]}

Schemitsch, Emil H. ^{[1
]}

机构：

[1] Univ Toronto, Dept Surg, Div Orthopaed, St Michaels Hosp, Toronto, ON M5C 1R6, Canada

[2] Walter Reed Natl Mil Med Ctr, Dept Orthopaed & Rehabil, Bethesda, MD USA

[3] Carolinas Med Ctr, Dept Orthopaed Surg, Charlotte, ND USA

[4] Indiana Univ Sch Med, Dept Orthopaed Surg, Indianapolis, IN USA

[5] Hosp Univ Penn, Dept Orthopaed Surg, Philadelphia, PA 19104 USA

[6] Univ Calif San Francisco, Dept Orthopaed Surg, UCSF SFGH Orthopaed Trauma Inst, San Francisco Gen Hosp, San Francisco, CA USA

来源：

JOURNAL OF ORTHOPAEDIC TRAUMA | 2012年 / 26卷 / 12期

关键词：

heterotopic ossification; pathophysiology; prophylaxis; surgical treatment; radiation therapy; NSAIDs; blast injuries; traumatic brain injury; spinal cord injury; ACETABULAR FRACTURES; RADIATION-THERAPY; OPERATIVE TREATMENT; RISK-FACTORS; INDOMETHACIN; PROPHYLAXIS; EXCISION; ELBOW; BONE; SURGERY;

D O I：

10.1097/BOT.0b013e3182724624

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Heterotopic ossification (HO) can be defined as the pathologic formation of bone in extraskeletal tissues. There has been a substantial amount of recent research on the pathophysiology, prophylaxis, and treatment of HO and traumatic conditions associated with the development of HO. This research has advanced our understanding of this disease and helped to clarify evidence-based approaches to both the prophylaxis and treatment of HO. This article reviews the literature on these topics with a focus on their application in orthopaedic trauma.

引用

页码：684 / 688

页数：5

共 29 条

[1] A comparison of heterotopic ossification treatment within the traumatic brain and spinal cord injured population: An evidence based systematic review [J].

Aubut, Jo-Anne L. ;

Mehta, Swati ;

Cullen, Nora ;

Teasell, Robert W. .

NEUROREHABILITATION, 2011, 28 (02) :151-160

[2] Heterotopic ossification: Pathophysiology, clinical features, and the role of radiotherapy for prophylaxis [J].

Balboni, Tracy A. ;

Gobezie, Reuben ;

Mamon, Harvey J. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 65 (05) :1289-1299

[3] Is Radiation Superior to Indomethacin to Prevent Heterotopic Ossification in Acetabular Fractures?: A Systematic Review [J].

Blokhuis, Taco J. ;

Frolke, Jan Paul M. .

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2009, 467 (02) :526-530

[4] Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion [J].

Burd, TA ;

Hughes, MS ;

Anglen, JO .

JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2003, 85B (05) :700-705

[5] Indomethacin compared with localized irradiation for the prevention of heterotopic ossification following surgical treatment of acetabular fractures [J].

Burd, TA ;

Lowry, KJ ;

Anglen, JO .

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2001, 83A (12) :1783-1788

[6] Heterotopic Ossification Following Traumatic Brain Injury and Spinal Cord Injury [J].

Cipriano, Cara A. ;

Pill, Stephan G. ;

Keenan, Mary Ann .

JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 2009, 17 (11) :689-697

[7]

Davis TA, 2011, J BONE JOINT SURG AM, V93A, P1122, DOI [10.2106/JBJSJ.01417, 10.2106/JBJS.J.01417]

[8] Surgical management of posttraumatic elbow arthrofibrosis [J].

Ehsan, Amirhesam ;

Huang, Jerry I. ;

Lyons, Matt ;

Hanel, Douglas P. .

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2012, 72 (05) :1399-1403

[9] Inflammatory Cytokine and Chemokine Expression is Associated With Heterotopic Ossification in High-Energy Penetrating War Injuries [J].

Evans, Korboi N. ;

Forsberg, Jonathan A. ;

Potter, Benjamin K. ;

Hawksworth, Jason S. ;

Brown, Trevor S. ;

Andersen, Romney ;

Dunne, James R. ;

Tadaki, Douglas ;

Elster, Eric A. .

JOURNAL OF ORTHOPAEDIC TRAUMA, 2012, 26 (11) :E204-E213

[10]

Forsberg Jonathan Agner, 2010, J Surg Orthop Adv, V19, P54

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