Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone-boronic acid hybrids

被引：9

作者：

Takahashi, Daisuke ^{[1
]}

Miura, Takuya ^{[1
]}

Toshima, Kazunobu ^{[1
]}

机构：

[1] Keio Univ, Dept Appl Chem, Fac Sci & Technol, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 61期

关键词：

TARGET OLIGOSACCHARIDES; DEGRADATION; BACTERIAL;

D O I：

10.1039/c2cc33559j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Target-selective photodegradation of 3-deoxy-D-manno-2-octulopyranosonic acid (KDO) was achieved without additives and under neutral conditions using a designed anthraquinone-boronic acid hybrid and long wavelength UV light irradiation. The hybrid can photodegrade lipopolysaccharides (LPS) and inhibit macrophage activation induced by LPS.

引用

页码：7595 / 7597

页数：3