Ketamine: A new perspective for treatment of depression in supportive care?

被引：4

作者：

Lemaire, A. ^{[1
]}

Plancon, M. ^{[1
]}

Bubrovszky, M. ^{[2
]}

机构：

[1] Ctr Hosp Valenciennes, F-59322 Valenciennes, France

[2] CHRU Lille, Hop Fontan, Serv Psychiat Adulte, F-59037 Lille, France

来源：

PSYCHO-ONCOLOGIE | 2014年 / 8卷 / 01期

关键词：

Ketamine; Depression; Antidepressant; Cancer; Early palliative care; GLYCOGEN-SYNTHASE KINASE-3; D-ASPARTATE ANTAGONIST; ELECTROCONVULSIVE-THERAPY; PALLIATIVE CARE; DOSE KETAMINE; DOUBLE-BLIND; DEATH; ANTIDEPRESSANTS; PREVALENCE; ONCOLOGY;

D O I：

10.1007/s11839-014-0453-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Ketamine, a molecule mainly used as an analgesic in supportive oncology in particular in palliative care, turns out to be an excellent fast-acting antidepressant. By acting as an NMDA receptor antagonist, its mechanism of action is complementary to classical and long-acting antidepressants like selective serotonin reuptake inhibitors. These properties offer new perspectives in fast-controlling depression within the development of early palliative care in oncology.

引用

页码：59 / 67

页数：9

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