Ultrasensitive, Rapid, and Selective Detection of Mercury Using Graphene Assisted Laser Desorption/Ionization Mass Spectrometry

被引：54

作者：

Abdelhamid, Hani Nasser ^{[1
,2
]}

Wu, Hui-Fen ^{[1
,3
,4
,5
,6
]}

机构：

[1] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 804, Taiwan

[2] Assiut Univ, Dept Chem, Assiut 71515, Egypt

[3] Kaohsiung Med Univ, Sch Pharm, Coll Pharm, Kaohsiung 806, Taiwan

[4] Natl Sun Yat Sen Univ, Inst Med Sci & Technol, Kaohsiung 804, Taiwan

[5] Natl Sun Yat Sen Univ, Ctr Nanosci & Nanotechnol, Kaohsiung 804, Taiwan

[6] Natl Sun Yat Sen Univ, Doctoral Degree Program Marine Biotechnol, Kaohsiung 804, Taiwan

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2014年 / 25卷 / 05期

关键词：

Graphene; Mass spectrometry; Mercury; Biosensing; Selective; MALDI-TOF-MS; COLORIMETRIC DETECTION; PATHOGENIC BACTERIA; GOLD NANOPARTICLES; FLUORESCENT SENSOR; AQUEOUS-MEDIA; BASE-PAIRS; METAL-IONS; ONE-STEP; TURN-ON;

D O I：

10.1007/s13361-014-0825-z

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We report an extremely sensitive and specific detection of mercuric ions (Hg2+) based on graphene assisted laser desorption/ionization mass spectrometry (GALDI-MS). Combining the highly selective coordination interactions between thymine (T) and Hg2+, we present a simple, effective, and novel approach, based on pi-pi interactions of the T-Hg2+-T complex and G that can serve as a platform and matrix for GALDI-MS. The present sensor not only exhibits high selectivity and sensitivity (picomolar) to Hg2+ in aqueous solution, but also can elucidate the chemical structures of the metal complexes. The significant advantage in the current approach is that there is no need for a sophisticated instrument, and no sample pretreatment is required to detect the Hg2+ ions.

引用

页码：861 / 868

页数：8

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