Association of sarcopenia with phase angle and body mass index in kidney transplant recipients

被引：52

作者：

Kosoku, Akihiro ^{[1
]}

Uchida, Junji ^{[1
]}

Nishide, Shunji ^{[1
]}

Kabei, Kazuya ^{[1
]}

Shimada, Hisao ^{[1
]}

Iwai, Tomoaki ^{[1
]}

Maeda, Keiko ^{[2
]}

Hanayama, Yoshiko ^{[3
]}

Ishihara, Takuma ^{[4
]}

Naganuma, Toshihide ^{[1
]}

Takemoto, Yoshiaki ^{[1
]}

Nakatani, Tatsuya ^{[1
]}

机构：

[1] Osaka City Univ, Grad Sch Med, Dept Urol, Osaka 5458585, Japan

[2] Osaka City Univ Hosp, Dept Nursing, Osaka 5458586, Japan

[3] Osaka City Univ Hosp, Dept Nutr, Osaka 5458586, Japan

[4] Gifu Univ Hosp, Innovat & Clin Res Promot Ctr, Gifu 5011194, Japan

来源：

SCIENTIFIC REPORTS | 2020年 / 10卷 / 01期

关键词：

BIOELECTRICAL-IMPEDANCE ANALYSIS; ASIAN WORKING GROUP; QUALITY-OF-LIFE; RISK-FACTORS; ELDERLY-PATIENTS; CYSTATIN C; PREVALENCE; DEFINITION; DISABILITY; CREATININE;

D O I：

10.1038/s41598-019-57195-z

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Malnutrition is an important risk factor for the development of sarcopenia. Recently, phase angle (PhA) obtained from the bioelectrical impedance analysis is increasingly becoming known as a nutritional status marker and may be considered a good indicator to identify elderly patients at risk of sarcopenia. In this study, we investigated the prevalence of sarcopenia and the relationship between sarcopenia and PhA or body mass index (BMI) as nutritional factors, and evaluated the discrimination performance of these nutritional factors for sarcopenia in 210 kidney transplant recipients. The median age was 55 years and 11.1% had sarcopenia. This prevalence of sarcopenia was lower than previous reports in kidney transplant recipients, maybe because of the differences in sarcopenia definitions and population demographics such as age, sex, race, and comorbidities. Both PhA and BMI were negatively correlated with sarcopenia after adjusting for age, sex, dialysis vintage, time after transplant, presence of diabetes mellitus, hemoglobin, estimated glomerular filtration rate, and the other nutritional factor. The discrimination performance for PhA and BMI had enough power to detect sarcopenia. These results suggest that PhA and BMI can be used in clinical practice to predict sarcopenia in kidney transplant patients.

引用

页数：8

共 45 条

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