How do maternal factors impact preeclampsia prediction in Brazilian population?

被引:6
作者
de Castro Rezende, Karina Bilda [1 ,2 ]
Ledo Alves da Cunha, Antonio Jose [3 ,4 ]
Pritsivelis, Cristos [1 ]
Faleiro, Edson Chaves [1 ]
Amim Junior, Joffre [1 ,2 ]
Bornia, Rita Guerios [1 ,2 ]
机构
[1] Univ Fed Rio de Janeiro, Maternidade Escola, Rio De Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Rio De Janeiro, Brazil
[3] Univ Fed Rio de Janeiro, Fac Med, Rio De Janeiro, Brazil
[4] Univ Fed Rio de Janeiro, Lab Multidisciplinar Pesquisa Epidemiol & Saude, Rio De Janeiro, Brazil
关键词
First trimester screening; maternal history; preeclampsia; risk factors; HYPERTENSIVE DISORDERS; PREGNANCY; ASPIRIN; RISK;
D O I
10.1080/14767058.2017.1399115
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To evaluate the impacts of maternal risk factors described by the Fetal Medicine Foundation's 2012 algorithm (FMF2012) in a Brazilian population. Methods: All singleton pregnancies submitted to first-trimester preeclampsia (PE) screening using the FMF2012 algorithm were considered for study inclusion. Maternal factors, recorded via a patient questionnaire, were described and compared between PE outcome groups. A Gaussian regression model was derived to measure the effects of maternal factors, and to identify factors that contributed significantly (p < .05) to the alteration of gestational age at delivery, in pregnancies with PE. Results: Of the 1934 cases considered for study inclusion, the final sample consisted of 1531 cases. The sample included 120 (7.8%) cases of PE, of which 26 (1.7%) were preterm PE (PE < 37 weeks) and 11 (0.72%) were early PE (PE < 34 weeks). The PE rate did not differ according to ethnicity, smoking, family history of PE, or use of assisted reproductive technology. Significant differences (p < .05) between the normal and PE groups in maternal age, maternal weight, previous history of PE, chronic hypertension, and types 1 and 2 diabetes were detected. Conclusions: The significance and magnitude of associations of maternal factors in our sample differed from those incorporated in the FMF2012 model, implying the need to derive a fitted model for our population.
引用
收藏
页码:1051 / 1056
页数:6
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