Recent Progress on Electron Capture Dissociation Mass Spectrometry

被引：0

作者：

Wang Ze ^{[1
,2
]}

Wong, Y-L. Elaine ^{[2
]}

Ren Juan ^{[1
]}

Chen Xiangfeng ^{[2
,3
]}

Chan, T-W. Dominic ^{[2
]}

机构：

[1] Zunyi Med Univ, Key Lab Fundamental & Appl Res Tradit Chinese Med, Zhuhai Campus, Zhuhai 519090, Peoples R China

[2] Chinese Univ Hong Kong, Dept Chem, Hong Kong, Peoples R China

[3] Shandong Acad Sci, Instrumental Anal & Testing Ctr, Jinan 250014, Shandong, Peoples R China

来源：

ACTA CHIMICA SINICA | 2019年 / 77卷 / 02期

基金：

中国国家自然科学基金;

关键词：

mass spectrometry; electron capture dissociation; gas phase ion chemistry; protein characterization; COLLISION-INDUCED DISSOCIATION; DISULFIDE BOND-CLEAVAGE; INFRARED MULTIPHOTON DISSOCIATION; PEPTIDE CATION-RADICALS; AMINO-ACID-RESIDUES; TOP-DOWN; PROTEIN IDENTIFICATION; ION/ION REACTIONS; ULTRAVIOLET PHOTODISSOCIATION; STRUCTURAL-CHARACTERIZATION;

D O I：

10.6023/A18090363

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the past twenty years, our knowledge on gas phase radical ion chemistry has been significantly improved due to the development of electron capture dissociation. Combined with soft ionization method, it has shown the technique can provide novel fragment ions for the structural elucidation of biomolecules, especially for protein characterization. This review aims to introduce fundamental aspects of electron capture dissociation mass spectrometry, as well as its applications in the analysis of biomolecules.

引用

页码：130 / 142

页数：13

共 141 条

[21] Protein identification using sequential ion/ion reactions and tandem mass spectrometry [J].

Coon, JJ ;

Ueberheide, B ;

Syka, JEP ;

Dryhurst, DD ;

Ausio, J ;

Shabanowitz, J ;

Hunt, DF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (27) :9463-9468

[22] The role of electron capture dissociation in biomolecular analysis [J].

Cooper, HJ ;

Håkansson, K ;

Marshall, AG .

MASS SPECTROMETRY REVIEWS, 2005, 24 (02) :201-222

[23] Investigating macromolecular complexes using top-down mass spectrometry [J].

Erba, Elisabetta Boeri .

PROTEOMICS, 2014, 14 (10) :1259-1270

[24] ELECTROSPRAY IONIZATION FOR MASS-SPECTROMETRY OF LARGE BIOMOLECULES [J].

FENN, JB ;

MANN, M ;

MENG, CK ;

WONG, SF ;

WHITEHOUSE, CM .

SCIENCE, 1989, 246 (4926) :64-71

[25] Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation [J].

Fischle, W ;

Tseng, BS ;

Dormann, HL ;

Ueberheide, BM ;

Garcia, BA ;

Shabanowitz, J ;

Hunt, DF ;

Funabiki, H ;

Allis, CD .

NATURE, 2005, 438 (7071) :1116-1122

[26] Top-Down Deep Sequencing of Ubiquitin Using Two-Dimensional Mass Spectrometry [J].

Floris, Federico ;

Chiron, Lionel ;

Lynch, Alice M. ;

Barrow, Mark P. ;

Delsuc, Marc-Andre ;

O'Connor, Peter B. .

ANALYTICAL CHEMISTRY, 2018, 90 (12) :7302-7309

[27] Exploiting the kernel trick to correlate fragment ions for peptide identification via tandem mass spectrometry [J].

Fu, Y ;

Yang, Q ;

Sun, RX ;

Li, DQ ;

Zeng, R ;

Ling, CX ;

Gao, W .

BIOINFORMATICS, 2004, 20 (12) :1948-1954

[28] Electron capture dissociation of peptides metalated with alkaline-earth metal ions [J].

Fung, Y. M. Eva ;

Liu, Haichuan ;

Chan, T. -W. Dominic .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2006, 17 (06) :757-771

[29] Electron Ionization Dissociation of Singly and Multiply Charged Peptides [J].

Fung, Y. M. Eva ;

Adams, Christopher M. ;

Zubarev, Roman A. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (29) :9977-9985

[30] Facile disulfide bond cleavage in gaseous peptide and protein cations by ultraviolet photodissociation at 157 nm [J].

Fung, YME ;

Kjeldsen, F ;

Silivra, OA ;

Chan, TWD ;

Zubarev, RA .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (39) :6399-6403

← 1 2 3 4 5 6 7 8 9 10 →