Recent Progress on Electron Capture Dissociation Mass Spectrometry

被引：0

作者：

Wang Ze ^{[1
,2
]}

Wong, Y-L. Elaine ^{[2
]}

Ren Juan ^{[1
]}

Chen Xiangfeng ^{[2
,3
]}

Chan, T-W. Dominic ^{[2
]}

机构：

[1] Zunyi Med Univ, Key Lab Fundamental & Appl Res Tradit Chinese Med, Zhuhai Campus, Zhuhai 519090, Peoples R China

[2] Chinese Univ Hong Kong, Dept Chem, Hong Kong, Peoples R China

[3] Shandong Acad Sci, Instrumental Anal & Testing Ctr, Jinan 250014, Shandong, Peoples R China

来源：

ACTA CHIMICA SINICA | 2019年 / 77卷 / 02期

基金：

中国国家自然科学基金;

关键词：

mass spectrometry; electron capture dissociation; gas phase ion chemistry; protein characterization; COLLISION-INDUCED DISSOCIATION; DISULFIDE BOND-CLEAVAGE; INFRARED MULTIPHOTON DISSOCIATION; PEPTIDE CATION-RADICALS; AMINO-ACID-RESIDUES; TOP-DOWN; PROTEIN IDENTIFICATION; ION/ION REACTIONS; ULTRAVIOLET PHOTODISSOCIATION; STRUCTURAL-CHARACTERIZATION;

D O I：

10.6023/A18090363

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the past twenty years, our knowledge on gas phase radical ion chemistry has been significantly improved due to the development of electron capture dissociation. Combined with soft ionization method, it has shown the technique can provide novel fragment ions for the structural elucidation of biomolecules, especially for protein characterization. This review aims to introduce fundamental aspects of electron capture dissociation mass spectrometry, as well as its applications in the analysis of biomolecules.

引用

页码：130 / 142

页数：13

共 141 条

[1] Distinguishing and quantifying peptides and proteins containing D-amino acids by tandem mass spectrometry [J].

Adams, CM ;

Zubarev, RA .

ANALYTICAL CHEMISTRY, 2005, 77 (14) :4571-4580

[2] Electron capture dissociation distinguishes a single D-amino acid in a protein and probes the tertiary structure [J].

Adams, CM ;

Kjeldsen, F ;

Zubarev, RA ;

Budnik, BA ;

Haselmann, KF .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2004, 15 (07) :1087-1098

[3]

[Anonymous], 1993, Interpretation of Mass Spectra, universitty Science - books

[4] Electron capture dissociation in a radio frequency ion trap [J].

Baba, T ;

Hashimoto, Y ;

Hasegawa, H ;

Hirabayashi, A ;

Waki, I .

ANALYTICAL CHEMISTRY, 2004, 76 (15) :4263-4266

[5] CONTRIBUTIONS OF MASS-SPECTROMETRY TO PEPTIDE AND PROTEIN-STRUCTURE [J].

BIEMANN, K .

BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY, 1988, 16 (1-12) :99-111

[6] Sequence-Scrambling Fragmentation Pathways of Protonated Peptides [J].

Bleiholder, Christian ;

Osburn, Sandra ;

Williams, Todd D. ;

Suhai, Sandor ;

Van Stipdonk, Michael ;

Harrison, Alex G. ;

Paizs, Bela .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (52) :17774-17789

[7] Top-down tandem mass spectrometry on RNase A and B using a Qh/FT-ICR hybrid mass spectrometer [J].

Bourgoin-Voillard, Sandrine ;

Leymarie, Nancy ;

Costello, Catherine E. .

PROTEOMICS, 2014, 14 (10) :1174-1184

[8] Electron detachment dissociation of peptide di-anions: an electron-hole recombination phenomenon [J].

Budnik, BA ;

Haselmann, KF ;

Zubarev, RA .

CHEMICAL PHYSICS LETTERS, 2001, 342 (3-4) :299-302

[9] A Mechanistic Study of the Electron Capture Dissociation of Oligonucleotides [J].

Chan, Tak Wah Dominic ;

Choy, Man Fai ;

Chan, Wai Yi Kelly ;

Fung, Yi Man Eva .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2009, 20 (02) :213-226

[10] Optimization of experimental parameters for electron capture dissociation of peptides in a Fourier transform mass spectrometer [J].

Chan, TWD ;

Ip, WHH .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2002, 13 (12) :1396-1406

← 1 2 3 4 5 6 7 8 9 10 →