Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time

被引:3
作者
Hanedan, Muhammet Onur [1 ]
Yuruk, Mehmet Ali [1 ]
Arslan, Ali Kemal [1 ]
Kilic, Askin [1 ]
Sayar, Ufuk [1 ]
Mataraci, Ilker [1 ]
机构
[1] Univ Hlth Sci, Dept Cardiovasc Surg, Ahi Evren Thorac & Cardiovasc Surg Training & Res, Ahi Evren GKD EAH Soguksu Mahellesi, TR-61040 Trabzon, Turkey
关键词
Cardiopulmonary Bypass; Heparin; Hospital Mortality; Length of Stay; Erythrocyte Transfusion; Silver; Cardiac Surgical Procedures; Intensive Care Units; Postoperative Period; ANTICOAGULATION; IMPACT;
D O I
10.21470/1678-9741-2019-0387
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods: A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those receiving heparin-coated circuits (Bioline (R), Maquet Cardiopulmonary AG., Hirrlingen, Germany) and those receiving non-coated circuits (Maquet Cardiopulmonary AG., Hirrlingen, Germany). Results: Activated clotting times (ACT) during cardiopulmonary bypass (CPB) were significantly shorter in the heparin-albumin-coated group than in the non-coated group (355.64 +/- 34.12 vs. 560.38 +/- 90.20, respectively, P=0.001). In-hospital mortality and postoperative stroke rates and lengths of intensive care unit stay were similar between the groups; in contrast, in the heparin-albumin-coated group, patients had significantly better outcomes for hospital stay, drainage, and need for erythrocyte transfusion. Conclusion: Heparin-coated circuits and reduced level of systemic heparinization with 300 seconds of target ACT level in cardiac surgery under CPB are safe and result in a very satisfactory clinical course.
引用
收藏
页码:913 / 917
页数:5
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