Motor perseveration is an early sign of Parkinson's disease

被引：37

作者：

Stoffers, D

Berendse, HW

Deijen, JB

Wolters, EC

机构：

[1] Vrije Univ Amsterdam, Med Ctr, Dept Neurol, NL-1007 MB Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Dept Clin Neuropsychol, NL-1007 MB Amsterdam, Netherlands

来源：

NEUROLOGY | 2001年 / 57卷 / 11期

关键词：

D O I：

10.1212/WNL.57.11.2111

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Perseveration in the generation of random motor behavior as examined by means of the Vienna perseverance task in groups of de novo (n = 18) and treated (n = 18) patients with early PD, and in control subjects (n = 18). In comparison with control subjects, both the de novo and treated patients with PD were relatively unable to generate random motor sequences, indicating a decreased ability to switch cortical behavioral programs in PD. An impairment of random motor generation appears to be a very early feature of PD.

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页码：2111 / 2113

页数：3

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