The Conundrum of Platelet P2Y12 Inhibition in ST-Segment Elevation Myocardial Infarction

被引:3
作者
Rollini, Fabiana [1 ]
Franchi, Francesco [1 ]
机构
[1] Univ Florida, Coll Med Jacksonville, Jacksonville, FL 32209 USA
关键词
PERCUTANEOUS CORONARY INTERVENTION; ANTIPLATELET ACTION; PRIMARY PCI; PRASUGREL; TICAGRELOR; STEMI; CLOPIDOGREL; TABLETS; TRIAL; ONSET;
D O I
10.1253/circj.CJ-16-1063
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2429 / 2431
页数:3
相关论文
共 14 条
[1]   Onset of Antiplatelet Action With High (100 mg) Versus Standard (60 mg) Loading Dose of Prasugrel in Patients With ST-Segment-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention Pharmacodynamic Study [J].
Alexopoulos, Dimitrios ;
Makris, George ;
Xanthopoulou, Ioanna ;
Patsilinakos, Sotirios ;
Deftereos, Spyridon ;
Gkizas, Vassilios ;
Perperis, Angelos ;
Karanikas, Stavros ;
Angelidis, Christos ;
Tsigkas, Grigorios ;
Koutsogiannis, Nikolaos ;
Hahalis, George ;
Davlouros, Periklis .
CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 2014, 7 (02) :233-+
[2]   Double Versus Standard Loading Dose of Ticagrelor Onset of Antiplatelet Action in Patients With STEMI Undergoing Primary PCI [J].
Alexopoulos, Dimitrios ;
Gkizas, Vassilios ;
Patsilinakos, Sotirios ;
Xanthopoulou, Ioanna ;
Angelidis, Christos ;
Anthopoulos, Prodromos ;
Makris, George ;
Perperis, Angelos ;
Karanikas, Stavros ;
Koutsogiannis, Nikolaos ;
Davlouros, Periklis ;
Deftereos, Spyridon ;
Chiladakis, John ;
Hahalis, George .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 62 (10) :940-941
[3]   Randomized Assessment of Ticagrelor Versus Prasugrel Antiplatelet Effects in Patients with ST-Segment-Elevation Myocardial Infarction [J].
Alexopoulos, Dimitrios ;
Xanthopoulou, Ioanna ;
Gkizas, Vassilios ;
Kassimis, George ;
Theodoropoulos, Konstantinos C. ;
Makris, George ;
Koutsogiannis, Nikolaos ;
Damelou, Anastasia ;
Tsigkas, Grigorios ;
Davlouros, Periklis ;
Hahalis, George .
CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 2012, 5 (06) :797-804
[4]   Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events [J].
Bhatt, Deepak L. ;
Stone, Gregg W. ;
Mahaffey, Kenneth W. ;
Gibson, C. Michael ;
Steg, P. Gabriel ;
Hamm, Christian W. ;
Price, Matthew J. ;
Leonardi, Sergio ;
Gallup, Dianne ;
Bramucci, Ezio ;
Radke, Peter W. ;
Widimsky, Petr ;
Tousek, Frantisek ;
Tauth, Jeffrey ;
Spriggs, Douglas ;
McLaurin, Brent T. ;
Angiolillo, Dominick J. ;
Genereux, Philippe ;
Liu, Tiepu ;
Prats, Jayne ;
Todd, Meredith ;
Skerjanec, Simona ;
White, Harvey D. ;
Harrington, Robert A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (14) :1303-1313
[5]   Impact of Escalating Loading Dose Regimens of Ticagrelor in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention Results of a Prospective Randomized Pharmacokinetic and Pharmacodynamic Investigation [J].
Franchi, Francesco ;
Rollini, Fabiana ;
Cho, Jung Rae ;
Bhatti, Mona ;
DeGroat, Christopher ;
Ferrante, Elisabetta ;
Dunn, Elizabeth C. ;
Nanavati, Amit ;
Carraway, Edward ;
Suryadevara, Siva ;
Zenni, Martin M. ;
Guzman, Luis A. ;
Bass, Theodore A. ;
Angiolillo, Dominick J. .
JACC-CARDIOVASCULAR INTERVENTIONS, 2015, 8 (11) :1457-1467
[6]   Novel antiplatelet agents in acute coronary syndrome [J].
Franchi, Francesco ;
Angiolillo, Dominick J. .
NATURE REVIEWS CARDIOLOGY, 2015, 12 (01) :30-47
[7]   Pharmacodynamic Assessment of Platelet Reactivity After a Loading Dose of Prasugrel or Clopidogrel in Patients With ST-Segment Elevation Myocardial Infarction [J].
Ichikawa, Shinya ;
Tsukahara, Kengo ;
Minamimoto, Yugo ;
Kimura, Yuichiro ;
Matsuzawa, Yasushi ;
Maejima, Nobuhiko ;
Iwahashi, Noriaki ;
Hibi, Kiyoshi ;
Kosuge, Masami ;
Ebina, Toshiaki ;
Kimura, Kazuo .
CIRCULATION JOURNAL, 2016, 80 (12) :2520-+
[8]   Ticagrelor Crushed Tablets Administration in STEMI Patients [J].
Parodi, Guido ;
Xanthopoulou, Ioanna ;
Bellandi, Benedetta ;
Gkizas, Vassilios ;
Valenti, Renato ;
Karanikas, Stavros ;
Migliorini, Angela ;
Angelidis, Christos ;
Abbate, Rosanna ;
Patsilinakos, Sotirios ;
Baldereschi, Giorgio J. ;
Marcucci, Rossella ;
Gensini, Gian Franco ;
Antoniucci, David ;
Alexopoulos, Dimitrios .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 65 (05) :511-512
[9]   Crushed Prasugrel Tablets in Patients With STEMI Undergoing Primary Percutaneous Coronary Intervention [J].
Rollini, Fabiana ;
Franchi, Francesco ;
Hu, Jenny ;
Kureti, Megha ;
Aggarwal, Niti ;
Durairaj, Ashwin ;
Park, Yongwhi ;
Seawell, Michael ;
Cox-Alomar, Pedro ;
Zenni, Martin M. ;
Guzman, Luis A. ;
Suryadevara, Siva ;
Antoun, Patrick ;
Bass, Theodore A. ;
Angiolillo, Dominick J. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2016, 67 (17) :1994-2004
[10]   Efficacy and Safety of Adjusted-Dose Prasugrel Compared With Clopidogrel in Japanese Patients With Acute Coronary Syndrome - The PRASFIT-ACS Study [J].
Saito, Shigeru ;
Isshiki, Takaaki ;
Kimura, Takeshi ;
Ogawa, Hisao ;
Yokoi, Hiroyoshi ;
Nanto, Shinsuke ;
Takayama, Morimasa ;
Kitagawa, Kazuo ;
Nishikawa, Masakatsu ;
Miyazaki, Shunichi ;
Nakamura, Masato .
CIRCULATION JOURNAL, 2014, 78 (07) :1684-+