A catalyst- and solvent-free three-component reaction for the regioselective one-pot access to polyfunctionalized pyrroles

被引：29
|
作者：
Bhat, Subrahmanya Ishwar [1 ]
Trivedi, Darshak R. [1 ]
机构：
[1] Natl Inst Technol Karnataka NITK, Dept Chem, Supramol Chem Lab, Mangalore 575025, Karnataka, India
来源：
TETRAHEDRON LETTERS | 2013年 / 54卷 / 41期
关键词：
Pyrrole; 1,3-Dicarbonyls; Solvent-free; One-pot; Three-component; Green chemistry; BIOLOGICAL EVALUATION; DERIVATIVES; EFFICIENT; INHIBITORS; ALKALOIDS; ROUTE;
D O I：
10.1016/j.tetlet.2013.07.153
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile method for the regioselective synthesis of tetrasubstituted pyrroles, from readily accessible 1,3-dicarbonyls, benzoin derivatives and ammonium acetate, has been developed. The one-pot three-component reactions were performed to afford tetrasubstituted pyrroles under solvent- and catalyst-free conditions. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5577 / 5582
页数：6
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