Synthesis and neurotropic activity of new condensed pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine derivatives

被引：2

作者：

Dabaeva, V. V. ^{[1
]}

Bagdasaryan, M. R. ^{[1
]}

Noravyan, A. S. ^{[1
]}

Dzhagatspanyan, I. A. ^{[1
]}

Nazaryan, I. N. ^{[1
]}

Akopyan, A. G. ^{[1
]}

机构：

[1] Natl Acad Sci Armenia, Mndzhoyan Inst Fine Organ Chem, Sci & Technol Ctr Organ & Pharmaceut Chem, Yerevan 375014, Armenia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2012年 / 46卷 / 05期

关键词：

synthesis; pyrido[3 ',2 ':4,5]thieno[3,2-d]pyrimidine; neurotropic activity; ELEVATED PLUS-MAZE;

D O I：

10.1007/s11094-012-0778-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Methods for the synthesis of derivatives of new pyrano[3",4":5',6']pyrido[3',2':4,5]thieno[3,2-d ]pyridimdine heterosystems based on 4-oxo-7,8-dihydro-2,8,8-trimethyl-10H-pyrano[3',4':5,6]pyrido[3,2:4",5"]thieno[3",2"-d]oxazine[3,1] were developed. The neurotropic activity of the synthesized compounds was investigated.

引用

页码：271 / 273

页数：3

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