Enootic and Epizootic Rabies Associated with Vampire Bats, Peru

被引：48

作者：

Edgar Condori-Condori, Rene ^{[1
,2
,3
]}

Streicker, Daniel G. ^{[1
,2
]}

Cabezas-Sanchez, Cesar ^{[3
]}

Velasco-Villa, Andres ^{[2
]}

机构：

[1] Univ Georgia, Athens, GA 30602 USA

[2] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

[3] Ctr Nacl Salud Publ, Inst Nacl Salud, Lima, Peru

来源：

EMERGING INFECTIOUS DISEASES | 2013年 / 19卷 / 09期

关键词：

GENETIC-CHARACTERIZATION; SAO-PAULO; VIRUS; BRAZIL; POLYMORPHISM; DIVERSITY; INFECTION; COUNTRIES; EXPOSURE; ECOLOGY;

D O I：

10.3201/eid1909.130083

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During the past decade, incidence of human infection with rabies virus (RABV) spread by the common vampire bat (Desmodus rotundus) increased considerably in South America, especially in remote areas of the Amazon rainforest, where these bats commonly feed on humans. To better understand the epizootiology of rabies associated with vampire bats, we used complete sequences of the nucleoprotein gene to infer phylogenetic relationships among 157 RABV isolates collected from humans, domestic animals, and wildlife, including bats, in Peru during 2002-2007. This analysis revealed distinct geographic structuring that indicates that RABVs spread gradually and involve different vampire bat subpopulations with different transmission cycles. Three putative new RABV lineages were found in 3 non vampire bat species that may represent new virus reservoirs. Detection of novel RABV variants and accurate identification of reservoir hosts are critically important for the prevention and control of potential virus transmission, especially to humans.

引用

页码：1463 / 1469

页数：7

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