A Sleep Apnea Detection System Based on a One-Dimensional Deep Convolution Neural Network Model Using Single-Lead Electrocardiogram

被引:82
作者
Chang, Hung-Yu [1 ,2 ]
Yeh, Cheng-Yu [3 ]
Lee, Chung-Te [3 ]
Lin, Chun-Cheng [3 ]
机构
[1] Cheng Hsin Gen Hosp, Heart Ctr, Taipei 112, Taiwan
[2] Natl Yang Ming Univ, Sch Med, Fac Med, Taipei 112, Taiwan
[3] Natl Chin Yi Univ Technol, Dept Elect Engn, Taichung 41170, Taiwan
关键词
obstructive sleep apnea; single-lead electrocardiogram; deep learning; convolutional neural network; CLASSIFICATION; ALGORITHM;
D O I
10.3390/s20154157
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Many works in recent years have been focused on developing a portable and less expensive system for diagnosing patients with obstructive sleep apnea (OSA), instead of using the inconvenient and expensive polysomnography (PSG). This study proposes a sleep apnea detection system based on a one-dimensional (1D) deep convolutional neural network (CNN) model using the single-lead 1D electrocardiogram (ECG) signals. The proposed CNN model consists of 10 identical CNN-based feature extraction layers, a flattened layer, 4 identical classification layers mainly composed of fully connected networks, and a softmax classification layer. Thirty-five released and thirty-five withheld ECG recordings from the MIT PhysioNet Apnea-ECG Database were applied to train the proposed CNN model and validate its accuracy for the detection of the apnea events. The results show that the proposed model achieves 87.9% accuracy, 92.0% specificity, and 81.1% sensitivity for per-minute apnea detection, and 97.1% accuracy, 100% specificity, and 95.7% sensitivity for per-recording classification. The proposed model improves the accuracy of sleep apnea detection in comparison with several feature-engineering-based and feature-learning-based approaches.
引用
收藏
页码:1 / 15
页数:15
相关论文
共 26 条
[1]  
[Anonymous], 2015, Tiny ImageNet Visual Recognition Challenge., DOI DOI 10.1109/ICCV.2015.123
[2]   Obstructive sleep apnea detection using spectrum and bispectrum analysis of single-lead ECG signal [J].
Atri, Roozbeh ;
Mohebbi, Maryam .
Physiological Measurement, 2015, 36 (09) :1963-1980
[3]  
Brevdo E., 2016, TENSOR
[4]   The indications for polysomnography and related procedures [J].
Chesson, AL ;
Ferber, RA ;
Fry, JM ;
GriggDamberger, M ;
Hartse, KM ;
Hurwitz, TD ;
Johnson, S ;
Kader, GA ;
Littner, M ;
Rosen, G ;
Sangal, RB ;
SchmidtNowara, W ;
Sher, A .
SLEEP, 1997, 20 (06) :423-487
[5]   Sleep-related breathing disorders in adults: Recommendations for syndrome definition and measurement techniques in clinical research [J].
Flemons, WW ;
Buysse, D ;
Redline, S ;
Pack, A ;
Strohl, K ;
Wheatley, J ;
Young, T ;
Douglas, N ;
Levy, P ;
McNicholas, W ;
Fleetham, J ;
White, D ;
Schmidt-Nowarra, W ;
Carley, D ;
Romaniuk, J .
SLEEP, 1999, 22 (05) :667-689
[6]   PhysioBank, PhysioToolkit, and PhysioNet - Components of a new research resource for complex physiologic signals [J].
Goldberger, AL ;
Amaral, LAN ;
Glass, L ;
Hausdorff, JM ;
Ivanov, PC ;
Mark, RG ;
Mietus, JE ;
Moody, GB ;
Peng, CK ;
Stanley, HE .
CIRCULATION, 2000, 101 (23) :E215-E220
[7]  
Griner P F, 1981, Ann Intern Med, V94, P557
[8]   An expert system for automated identification of obstructive sleep apnea from single-lead ECG using random under sampling boosting [J].
Hassan, Ahnaf Rashik ;
Haque, Md Aynal .
NEUROCOMPUTING, 2017, 235 :122-130
[9]   Sleep Apnea Severity Classification - Revisited [J].
Hudgel, David W. .
SLEEP, 2016, 39 (05) :1165-1166
[10]   Sleep Apnea Types, Mechanisms, and Clinical Cardiovascular Consequences [J].
Javaheri, Shahrokh ;
Barbe, Ferran ;
Campos-Rodriguez, Francisco ;
Dempsey, Jerome A. ;
Khayat, Rami ;
Javaheri, Sogol ;
Malhotra, Atul ;
Martinez-Garcia, Miguel A. ;
Mehra, Reena ;
Pack, Allan I. ;
Polotsky, Vsevolod Y. ;
Redline, Susan ;
Somers, Virend K. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2017, 69 (07) :841-858