The Unique Simultaneous Occurrence of a Squamous Cell Carcinoma and a Granular Cell Tumor of the Tongue at the Same Site: A Histological and Immunohistochemical Study

被引：9

作者：

Caltabiano, Rosario ^{[1
]}

Cappellani, Alessandro ^{[2
]}

Di Vita, Maria ^{[2
]}

Lanzafame, Salvatore ^{[1
]}

机构：

[1] Univ Catania, Sect Anat Pathol, Dept GF Ingrassia, I-95123 Catania, Italy

[2] Univ Catania, Dept Surg, I-95123 Catania, Italy

来源：

JOURNAL OF CRANIOFACIAL SURGERY | 2008年 / 19卷 / 06期

关键词：

Granular cell tumor; squamous cell carcinoma; tongue; p63; immunohistochemistry;

D O I：

10.1097/SCS.0b013e31818973ad

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

We report a case of a 47-year-old man with a granular cell tumor (GCT) of the tongue colocalized with a squamous cell carcinoma. To our knowledge, this is the first case to be reported in the literature with such an association. Furthermore, we performed an immunohistochemical analysis with p63 to distinguish pseudoepitheliomatous hyperplasia from invasive squamous cell carcinoma. Clinicians and pathologists must be made aware of this potential diagnostic pitfall so that the workup of a tongue lesion does not end prematurely with a benign diagnosis of granular cell tumor with overlying pseudoepitheliomatous hyperplasia.

引用

页码：1691 / 1694

页数：4

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