Precise control of the size and noise of solid-state nanopores using high electric fields

被引：80

作者：

Beamish, Eric ^{[1
]}

Kwok, Harold ^{[1
]}

Tabard-Cossa, Vincent ^{[1
]}

Godin, Michel ^{[1
]}

机构：

[1] Univ Ottawa, Dept Phys, Ottawa, ON K1N 6N5, Canada

来源：

NANOTECHNOLOGY | 2012年 / 23卷 / 40期

基金：

加拿大自然科学与工程研究理事会; 加拿大创新基金会;

关键词：

SURFACE; BEAM; TRANSLOCATION; FABRICATION;

D O I：

10.1088/0957-4484/23/40/405301

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

We present a methodology for preparing silicon nitride nanopores that provides in situ control of size with sub-nanometer precision while simultaneously reducing electrical noise by up to three orders of magnitude through the cyclic application of high electric fields in an aqueous environment. Over 90% of nanopores treated with this technique display desirable noise characteristics and readily exhibit translocation of double-stranded DNA molecules. Furthermore, previously used nanopores with degraded electrical properties can be rejuvenated and used for further single-molecule experiments.

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页数：7

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