Microwave initiated reactions: Pechmann coumarin synthesis, Biginelli reaction and acylation

被引：95

作者：

Manhas, MS ^{[1
]}

Ganguly, SN ^{[1
]}

Mukherjee, S ^{[1
]}

Jain, AK ^{[1
]}

Bose, AK ^{[1
]}

机构：

[1] Stevens Inst Technol, Dept Chem & Chem Biol, George Barasch Bioorgan Res Lab, Hoboken, NJ 07030 USA

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 14期

关键词：

D O I：

10.1016/j.tetlet.2006.01.147

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An energy-efficient protocol has been developed for solvent-free reactions that are mildly exothermic but not spontaneous. The exothermic reaction mixture-on several g-scale-is exposed For about 30 s to low power (about 200 W) microwaves and then the microwave oven is switched off. After this short burst of energy, the exothermic reaction gets initiated and proceeds on its own to completion. A number of coumarins were synthesized by the Pechmann reaction using this strategy. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：2423 / 2425

页数：3

共 7 条

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