CNS vasculitis in children

被引：17

作者：

Twilt, Marinka ^{[1
]}

Benseler, Susanne M. ^{[1
]}

机构：

[1] Univ Toronto, Hosp Sick Children, Res Inst, Div Rheumatol,Dept Pediat, Toronto, ON M5G 1X8, Canada

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2013年 / 2卷 / 03期

关键词：

cPACNS; Childhood primary angiitis of the central nervous system; CNS vasculitis; Childhood; Vascutitis; Inflammatory brain disease; CENTRAL-NERVOUS-SYSTEM; ACUTE DISSEMINATED ENCEPHALOMYELITIS; MAGNETIC-RESONANCE ANGIOGRAPHY; INHERITED METABOLIC-DISORDERS; ARTERIAL ISCHEMIC-STROKE; PRIMARY ANGIITIS; MULTIPLE-SCLEROSIS; NEUROMYELITIS-OPTICA; NEUROLOGIC MANIFESTATIONS; WEGENERS-GRANULOMATOSIS;

D O I：

10.1016/j.msard.2012.11.002

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Inflammatory brain diseases in childhood are underrecognized and lead to life-threatening neurological deficits. Early recognition and diagnosis of inflammatory brain diseases is critical, as the reversibility of the neurological deficits is closely related to early initiation of treatment and prevention of secondary brain tissue damage. Primary childhood CNS vasculitis is the most common cause of inflammatory brain disease in childhood. Clinical features, laboratory tests and imaging can be non-conclusive and overlap with other inflammatory brain diseases, such as demyelinating diseases. This review focuses on recent publications on epidemiology, pathogenesis, and treatment in childhood CNS vasculitis and relevant publications from the rapidly expanding differential diagnosis for the subtypes of CNS vasculitis, particularly the demyelinating brain diseases. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：162 / 171

页数：10

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