First application of fac-[99mTc(OH2)3(CO)3]+ in bioorganometallic chemistry:: Design, structure, and in vitro affinity of a 5-HT1A receptor ligand labeled with 99mTc

被引：207

作者：

Alberto, R

Schibli, R

Schubiger, AP ^{[1
]}

Abram, U

Pietzsch, HJ

Johannsen, B

机构：

[1] Paul Scherrer Inst, Ctr Radiopharm, CH-5232 Villigen, Switzerland

[2] Forschungszentrum Rossendorf EV, Inst Radiochem, D-01314 Dresden, Germany

[3] Forschungszentrum Rossendorf EV, Inst Radiopharmaceut & Bioinorgan Chem, D-01314 Dresden, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1999年 / 121卷 / 25期

关键词：

D O I：

10.1021/ja990765a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：6076 / 6077

页数：2

共 29 条

[1] Trans- and cis-water reactivities in d6 octahedral ruthenium(II) pentaaqua complexes:: Experimental and density functional theory studies [J].

Aebischer, N ;

Sidorenkova, E ;

Ravera, M ;

Laurenczy, G ;

Osella, D ;

Weber, J ;

Merbach, AE .

INORGANIC CHEMISTRY, 1997, 36 (26) :6009-6020

[2] METAL-CARBONYL SYNTHESES .22. LOW-PRESSURE CARBONYLATION OF [MOCL(4)](-) AND [MO4](-) - THE TECHNETIUM(I) AND RHENIUM(I) COMPLEXES [NET(4)](2)[MCL(3)(CO)(3)] [J].

ALBERTO, R ;

SCHIBLI, R ;

EGLI, A ;

SCHUBIGER, PA ;

HERRMANN, WA ;

ARTUS, G ;

ABRAM, U ;

KADEN, TA .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1995, 493 (1-2) :119-127

[3] A novel organometallic aqua complex of technetium for the labeling of biomolecules:: Synthesis of [99mTc(OH2)3(CO)3]+ from [99mTcO4]- in aqueous solution and its reaction with a bifunctional ligand [J].

Alberto, R ;

Schibli, R ;

Egli, A ;

Schubiger, AP ;

Abram, U ;

Kaden, TA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (31) :7987-7988

[4]

ALBERTO R, Patent No. 9848848

[5]

[Anonymous], 1991, SEROTONIN RECEPTOR S

[6] Bioorganometallic chemistry .8. The molecular recognition of aromatic and aliphatic amino acids and substituted aromatic and aliphatic carboxylic acid guests with supramolecular (eta(5)-pentamethylcyclopentadienyl)rhodium-nucleobase, nucleoside, and nucleotide cyclic trimer hosts via non-covalent pi-pi and hydrophobic interactions in water: Steric, electronic, and conformational parameters [J].

Chen, H ;

Ogo, S ;

Fish, RH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (21) :4993-5001

[7]

Cliffe Ian A., 1993, Drugs of the Future, V18, P631

[8] THE CHEMISTRY OF RHENIUM AND TECHNETIUM AS RELATED TO THE USE OF ISOTOPES OF THESE ELEMENTS IN THERAPEUTIC AND DIAGNOSTIC NUCLEAR-MEDICINE [J].

DEUTSCH, E ;

LIBSON, K ;

VANDERHEYDEN, JL ;

KETRING, AR ;

MAXON, HR .

NUCLEAR MEDICINE AND BIOLOGY, 1986, 13 (04) :465-477

[9] RADIOMETAL LABELING OF RECOMBINANT PROTEINS BY A GENETICALLY-ENGINEERED MINIMAL CHELATION SITE - TC-99M COORDINATION BY SINGLE-CHAIN FV ANTIBODY FUSION PROTEINS THROUGH A C-TERMINAL CYSTEINYL PEPTIDE [J].

GEORGE, AJT ;

JAMAR, F ;

TAI, MS ;

HEELAN, BT ;

ADAMS, GP ;

MCCARTNEY, JE ;

HOUSTON, LL ;

WEINER, LM ;

OPPERMANN, H ;

PETERS, AM ;

HUSTON, JS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (18) :8358-8362

[10] CONCEPTS FOR THE DESIGN OF 5-HT(1A) SEROTONIN AGONISTS AND ANTAGONISTS [J].

GLENNON, RA .

DRUG DEVELOPMENT RESEARCH, 1992, 26 (03) :251-274

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