TNF superfamily in skin appendage development

被引:64
作者
Mikkola, Marja L. [1 ]
机构
[1] Univ Helsinki, Dev Biol Program, Inst Biotechnol, FIN-00014 Helsinki, Finland
关键词
morphogenesis; placode; bud; ectodermal dysplasia; Edar; NF-kappa B;
D O I
10.1016/j.cytogfr.2008.04.008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The development of skin appendages such as hairs, teeth, and mammary glands is regulated by signaling molecules of the Wnt, FGF, TGF beta, and Hedgehog pathways. Last decade has also revealed a pivotal role for the TNF family ligand ectodysplasin (Eda) in multiple steps of epithelial appendage morphogenesis, from initiation to differentiation. Surprisingly, other members of the TNF superfamily such as Rank ligand, lymphotoxins, and TNF have recently been linked with specific aspects of skin appendage biology including branching of the mammary gland, hair shaft formation, and hair follicle cycling. This review focuses on the novel discoveries of Eda and other TNF related cytokines in skin appendage development made since the previous review on this topic in Cytokine and Growth Factor reviews in 2003. (c) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:219 / 230
页数:12
相关论文
共 80 条
[1]   Autosomal dominant anhidrotic ectodermal dysplasias at the EDARADD locus [J].
Bal, E. ;
Baala, L. ;
Cluzeau, C. ;
El Kerch, E. ;
Ouldim, K. ;
Hadj-Rabia, S. ;
Bodemer, C. ;
Munnich, A. ;
Courtois, G. ;
Sefiani, A. ;
Smahi, A. .
HUMAN MUTATION, 2007, 28 (07) :703-709
[2]   Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human [J].
Bossen, Claudia ;
Ingold, Karine ;
Tardivel, Aubry ;
Bodmer, Jean-Luc ;
Gaide, Olivier ;
Hertig, Sylvie ;
Ambrose, Christine ;
Tschopp, Juerg ;
Schneider, Pascal .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (20) :13964-13971
[3]   Alveolar and lactogenic differentiation [J].
Brisken, Cathrin ;
Rajaram, Renuga Devi .
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 2006, 11 (3-4) :239-248
[4]   Visualization of lymphotoxin-β and lymphotoxin-β receptor expression in mouse embryos [J].
Browning, JL ;
French, LE .
JOURNAL OF IMMUNOLOGY, 2002, 168 (10) :5079-5087
[5]   IKKα provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development [J].
Cao, YX ;
Bonizzi, G ;
Seagroves, TN ;
Greten, FR ;
Johnson, R ;
Schmidt, EV ;
Karin, M .
CELL, 2001, 107 (06) :763-775
[6]   Significant correction of disease after postnatal administration of recombinant ectodysplasin a in canine x-linked ectodermal dysplasia [J].
Casal, Margret L. ;
Lewis, John R. ;
Mauldin, Elizabeth A. ;
Tardivel, Aubry ;
Ingold, Karine ;
Favre, Manuel ;
Paradies, Fabrice ;
Demotz, Stephane ;
Gaide, Olivier ;
Schneider, Pascal .
AMERICAN JOURNAL OF HUMAN GENETICS, 2007, 81 (05) :1050-1056
[7]   Mutations in EDAR account for one-quarter of non-ED1-related hypohidrotic ectodermal dysplasia [J].
Chassaing, N ;
Bourthoumieu, S ;
Cosse, M ;
Calvas, P ;
Vincent, MC .
HUMAN MUTATION, 2006, 27 (03) :255-259
[8]   CLINICAL ASPECTS OF X-LINKED HYPOHIDROTIC ECTODERMAL DYSPLASIA [J].
CLARKE, A ;
PHILLIPS, DIM ;
BROWN, R ;
HARPER, PS .
ARCHIVES OF DISEASE IN CHILDHOOD, 1987, 62 (10) :989-996
[9]   Widespread parallel evolution in sticklebacks by repeated fixation of ectodysplasin alleles [J].
Colosimo, PF ;
Hosemann, KE ;
Balabhadra, S ;
Villarreal, G ;
Dickson, M ;
Grimwood, J ;
Schmutz, J ;
Myers, RM ;
Schluter, D ;
Kingsley, DM .
SCIENCE, 2005, 307 (5717) :1928-1933
[10]   NF-κB-related genetic diseases [J].
Courtois, G ;
Smahi, A .
CELL DEATH AND DIFFERENTIATION, 2006, 13 (05) :843-851