Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review

被引：6
|
作者：
Miyake, Keita [1 ]
Hara, Takashi [2 ]
Oshima, Etsuko [1 ]
Kawada, Kiyohiro [1 ]
Ishizu, Hideki [3 ]
Yamauchi, Yuko [3 ]
Satoh, Katsuya [4 ]
Kitamoto, Tetsuyuki [5 ]
Takenoshita, Shintaro [1 ]
Terada, Seishi [1 ]
Yamada, Norihito [1 ]
机构：
[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Psychiat, Kita Ku, 2-5-1 Shikata Cho, Okayama 7008558, Japan
[2] Hayashi Hosp, Dept Psychiat, Okayama, Japan
[3] Zikei Hosp, Dept Psychiat, Okayama, Japan
[4] Nagasaki Univ, Dept Locomot Rehabil Sci, Grad Sch Med, Nagasaki, Japan
[5] Tohoku Univ, Dept Neurol Sci, Grad Sch Med, Sendai, Miyagi, Japan
来源：
BMC NEUROLOGY | 2018年 / 18卷
关键词：
Alzheimer disease; Creutzfeldt-Jakob disease; Epilepsy; Seizuie; Status epilepticus; PRION DISEASES; COEXISTENCE; DIAGNOSIS; CONTINUA; JAPAN; CJD;
D O I：
10.1186/s12883-018-1055-y
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background: Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding. Case presentation: We experienced an elderly woman who presented initially with status epilepticus following repeated partial seizures in the course of Alzheimer disease (AD) dementia. Anti-convulsive therapy had no effect. Autopsy revealed definite CJD with AD pathology. Coclusions: This is the first reported CJD case presenting with status epilepticus in the course of AD dementia.
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页数：5
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