Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review

被引：6

作者：

Miyake, Keita ^{[1
]}

Hara, Takashi ^{[2
]}

Oshima, Etsuko ^{[1
]}

Kawada, Kiyohiro ^{[1
]}

Ishizu, Hideki ^{[3
]}

Yamauchi, Yuko ^{[3
]}

Satoh, Katsuya ^{[4
]}

Kitamoto, Tetsuyuki ^{[5
]}

Takenoshita, Shintaro ^{[1
]}

Terada, Seishi ^{[1
]}

Yamada, Norihito ^{[1
]}

机构：

[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Psychiat, Kita Ku, 2-5-1 Shikata Cho, Okayama 7008558, Japan

[2] Hayashi Hosp, Dept Psychiat, Okayama, Japan

[3] Zikei Hosp, Dept Psychiat, Okayama, Japan

[4] Nagasaki Univ, Dept Locomot Rehabil Sci, Grad Sch Med, Nagasaki, Japan

[5] Tohoku Univ, Dept Neurol Sci, Grad Sch Med, Sendai, Miyagi, Japan

来源：

BMC NEUROLOGY | 2018年 / 18卷

关键词：

Alzheimer disease; Creutzfeldt-Jakob disease; Epilepsy; Seizuie; Status epilepticus; PRION DISEASES; COEXISTENCE; DIAGNOSIS; CONTINUA; JAPAN; CJD;

D O I：

10.1186/s12883-018-1055-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding. Case presentation: We experienced an elderly woman who presented initially with status epilepticus following repeated partial seizures in the course of Alzheimer disease (AD) dementia. Anti-convulsive therapy had no effect. Autopsy revealed definite CJD with AD pathology. Coclusions: This is the first reported CJD case presenting with status epilepticus in the course of AD dementia.

引用

页数：5

共 50 条

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