Drug delivery systems for prolonged duration local anesthesia

被引:96
作者
Santamaria, Claudia M. [1 ]
Woodruff, Alan [1 ]
Yang, Rong [1 ]
Kohane, Daniel S. [1 ]
机构
[1] Boston Childrens Hosp, Dept Anesthesiol, Div Crit Care Med, Lab Biomat & Drug Delivery, Boston, MA 02115 USA
关键词
SCIATIC-NERVE BLOCKADE; PROTEIN-SUGAR PARTICLES; TRANSVERSUS ABDOMINIS PLANE; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; LIPOSOMAL BUPIVACAINE; CONTROLLED-RELEASE; IN-VIVO; POSTSURGICAL ANALGESIA; NEUROPATHIC PAIN;
D O I
10.1016/j.mattod.2016.11.019
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Numerous drug delivery systems have been applied to the problem of providing prolonged duration local anesthesia (PDLA). Here we review the rationale for PDLA, the desirable features for and important attributes of such systems, and specific examples that have been developed.
引用
收藏
页码:22 / 31
页数:10
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