Anaphylaxis in Latin American children and adolescents: The Online Latin American Survey on Anaphylaxis (OLASA)

被引:30
作者
Sole, D. [1 ]
Ivancevich, J. C. [2 ,3 ]
Borges, M. S. [4 ,5 ]
Coelho, M. A. [6 ]
Rosario, N. A. [7 ]
Ardusso, L. [8 ]
Bernd, L. A. G. [9 ]
机构
[1] Univ Fed Sao Paulo, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, Sao Paulo, Brazil
[2] Univ Salvador, Sch Med, Div Immunol, Buenos Aires, DF, Argentina
[3] Clin Santa Isabel, Div Allergy & Immunol, Buenos Aires, DF, Argentina
[4] Ctr Med Docente La Trinidad, Allergy & Clin Immunol Dept, Caracas, Venezuela
[5] Clin El Avila, Allergy & Immunol Dept, Caracas, Venezuela
[6] Univ Montes Claros, Dept Internal Med, Montes Claros, MG, Brazil
[7] Univ Fed Parana, Dept Pediat, BR-80060000 Curitiba, Parana, Brazil
[8] Natl Univ Rosario, Fac Med Sci, Div Med Pathol Pulmonol Allergy & Immunol 2, Rosario, Santa Fe, Argentina
[9] Fed Fac Fdn Med Sci Porto Alegre, Div Immunol & Immunopathol, Rio Grande Do Sul, Brazil
关键词
Anaphylaxis; Drugs; Food; Hymenoptera sp; Epinephrine; REVISED NOMENCLATURE; EPIDEMIOLOGY; ALLERGY;
D O I
10.1016/j.aller.2011.09.008
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Objectives: To identify the main clinical manifestations, triggers, and treatment of severe allergic reactions (SAR) in children and adolescents (n = 191, up to 18 years of age) seen by allergologists and registered in the Online Latin American Survey of Anaphylaxis (OLASA). Results: 53.0% of the patients were males and the aetiological agent was identified in 85.5% of them as follows: foods (36.1%), drugs (27.7%), and insect stings (26.2%). The most common symptoms during an acute episode were cutaneous (94.2%), and respiratory (78.5%). Most patients were treated in emergency setting, yet only 34.6% received parenteral epinephrine and 14.3% had to be hospitalised. Conclusion: Cutaneous symptoms ranked the order of clinical presentation of SAR. Food was the main triggering agent in the younger cases and insect sting and drugs in the adolescents. Treatment provided for SAR was not appropriate. It is necessary to improve educational programmes in order to enhance the knowledge on this potentially fatal emergency. (c) 2011 SEICAP. Published by Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码:331 / 335
页数:5
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