Liver involvement in dengue viral infections

被引：38
作者：
Dissanayake, Harsha A. [1 ]
Seneviratne, Suranjith L. [2 ,3 ,4 ]
机构：
[1] Natl Hosp Sri Lanka, Univ Med Unit, Colombo, Sri Lanka
[2] Royal Free Hosp, Inst Immun & Transplantat, London NW3 2QG, England
[3] UCL, London NW3 2QG, England
[4] Univ Colombo, Dept Surg, Fac Med, Colombo, Sri Lanka
来源：
REVIEWS IN MEDICAL VIROLOGY | 2018年 / 28卷 / 02期
关键词：
animal; dengue; human; liver; pathogenesis; VIRUS NONSTRUCTURAL PROTEIN-1; INTRAVENOUS N-ACETYLCYSTEINE; INDUCED CELL-DEATH; HEMORRHAGIC-FEVER; HEPATIC-DYSFUNCTION; CYTOKINE PRODUCTION; MEDIATED APOPTOSIS; FUNCTION TESTS; IN-VITRO; FAILURE;
D O I：
10.1002/rmv.1971
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Dengue fever is the commonest viral haemorrhagic fever worldwide and is a leading cause of morbidity and mortality in the tropics. Dengue viral infections are frequently associated with varying degrees of liver injury. Liver injury is more severe in dengue haemorrhagic fever or severe dengue. We review the current knowledge on liver involvement following dengue viral infections and explore the links between clinical manifestations, pathogenesis, and their impact on management
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页数：11
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