Psoriatic Arthritis in Canadian Clinical Practice: The PsA Assessment in Rheumatology

被引:10
作者
Gladman, Dafna D. [1 ]
Chandran, Vinod
Thavaneswaran, Arane [1 ]
Zummer, Michel [2 ]
机构
[1] Univ Toronto, Toronto Western Hosp, Univ Hlth Network, Toronto Western Res Inst,Psoriat Arthrit Program, Toronto, ON M5T 2S8, Canada
[2] Univ Montreal, Div Rheumatol, CH Maisonneuve Rosemont, Montreal, PQ, Canada
基金
加拿大健康研究院;
关键词
PSORIATIC ARTHRITIS; COMMUNITY CARE; TREATMENT; ACTIVITY; DAMAGE; SINGLE-CENTER; PROGRESSION; MORTALITY; DISEASE; TIME;
D O I
10.3899/jrheum.120282
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective. We aimed to determine disease severity and treatment of patients with psoriatic arthritis (PsA) in rheumatology practices in Canada through the PsA Assessment in Rheumatology (PAIR) study. Methods. Rheumatologists who were members of the Canadian Rheumatology Association were asked to complete a form for each patient addressing demographic questions, history, clinical examination, and patient-reported outcomes. Results were compared with a cohort seen in a PsA clinic during the same period. Results. From across Canada, 22 rheumatologists from 5 provinces submitted information about 233 consecutive patients with PsA [145 men (62.2%), 88 women (37.8%), mean age 53.2 yrs (+/- 12.7), 88.4% disease duration > 2 yrs]. A majority (80.7%) fulfilled ClASsification for Psoriatic ARthritis (CASPAR) criteria, and 30% had taken no disease-modifying antirheumatic drugs. Clinical joint damage was documented in 60% of the patients, active skin disease in 70%, and nail lesions in 32%. Only 22% were rated as having moderate to high disease activity, while 52% were rated as low disease activity and 26% were deemed in remission. The decision was based on joint counts, patient global assessment, physician global assessment, and acute-phase reactants. Twenty-seven percent of the patients were to have their medications changed based on the current visit, the majority for inadequate response to medications. Patients in the PAIR cohort had more inflamed joints but similar damage to those in the PsA clinic. Conclusion. Patients with PsA seen in regular rheumatology practice fulfill CASPAR criteria, have active disease, and more than half have joint damage. The majority have low activity or are in remission. (First Release Aug 1 2012; J Rheumatol 2012;39:1850-3; doi:10.3899/jrheum.120282)
引用
收藏
页码:1850 / 1853
页数:4
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