Cross-Linking Effect On Electrospun Hydroxyethyl Cellulose/Poly(Vinyl Alcohol) Nanofibrous Scaffolds

被引：19

作者：

Zulkifli, Farah Hanani ^{[1
]}

Shahitha, Fatimah ^{[1
]}

Yusuff, Mashitah Mohd ^{[1
]}

Hamidon, Nurul Nadiah ^{[1
]}

Chahal, Sugandha ^{[1
]}

机构：

[1] Univ Malaysia Pahang, Fak Sains & Teknol Ind, Kuantan 26300, Pahang Darul Ma, Malaysia

来源：

MALAYSIAN TECHNICAL UNIVERSITIES CONFERENCE ON ENGINEERING & TECHNOLOGY 2012 (MUCET 2012) | 2013年 / 53卷

关键词：

Crosslinking; Electrospinning; Hydroxyethyl cellulose; Nanofibers; Poly(vinyl alcohol); TISSUE; HYDROGELS; CARBOXYMETHYL; FABRICATION;

D O I：

10.1016/j.proeng.2013.02.089

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The electrospinning of hydroxyethyl cellulose/poly(vinyl alcohol) (HEC/PVA) was carried out with glutaraldehyde as a cross linker to fabricate water insoluble nanofibers. The concentration of HEC (5wt%) and PVA (15wt%) was prepared and blended in different weight ratios of HEC to PVA (50:50, 40:60 and 70:30) were electrospun to get nanofibers. The microstructure of the obtained nanofibers were analysed by scanning electron microscopy (SEM) and X-ray diffraction (XRD) before and after crosslinking. SEM images showed that there was no swelling or remarkable changes in the surface morphology after treated with glutaraldehyde. XRD analysis illustrated the effect of crosslinking on the crystallinity of the nanofibers. The results showed that these crosslinked HEC/PVA fibers were suitable for variety of applications such as tissue engineering scaffolds, drug delivery and medical prostheses. (C) 2013 The Authors. Published by Elsevier Ltd.

引用

页码：689 / 695

页数：7

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