Design of peptidomimetic ligands for the pp60(src) SH2 domain

被引：29
|
作者：
Plummer, MS
Lunney, EA
Para, KS
Shahripour, A
Stankovic, CJ
Humblet, C
Fergus, JH
Marks, JS
Herrera, R
Hubbell, S
Saltiel, A
Sawyer, TK
机构：
[1] PARKE DAVIS PHARMACEUT RES, DIV WARNER LAMBERT CO, DEPT CHEM, ANN ARBOR, MI 48106 USA
[2] PARKE DAVIS PHARMACEUT RES, DIV WARNER LAMBERT CO, DEPT BIOCHEM, ANN ARBOR, MI 48106 USA
[3] PARKE DAVIS PHARMACEUT RES, DIV WARNER LAMBERT CO, DEPT SIGNAL TRANSDUCT, ANN ARBOR, MI 48106 USA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY | 1997年 / 5卷 / 01期
关键词：
D O I：
10.1016/S0968-0896(96)00200-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Potent ligands of the Src SH2 domain, discovered through structure-based drug design efforts, with the general structure Ac-pTyr-Glu-NRR' are disclosed. Copyright (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：41 / 47
页数：7
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