Spatio-temporal correlation super-resolution optical fluctuation imaging

被引:7
作者
Purohit, A. [1 ]
Vandenberg, W. [2 ]
Dertinger, T. [3 ]
Woell, D. [1 ]
Dedecker, P. [2 ]
Enderlein, J. [3 ]
机构
[1] Rhein Westfal TH Aachen, Inst Phys Chem, Landoltweg 2, D-52074 Aachen, Germany
[2] Katholieke Univ Leuven, Dept Chem, Celestijnenlaan 200G, B-3001 Heverlee, Belgium
[3] Georg August Univ, Inst Phys Biophys 3, D-37077 Gottingen, Germany
关键词
RECONSTRUCTION MICROSCOPY; DIFFRACTION-LIMIT; RESOLUTION;
D O I
10.1209/0295-5075/125/20005
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We describe a new concept of multimodal super-resolution imaging which combines the cumulant analysis from Super-resolution Optical Fluctuation Imaging (SOFT) with the imprinting of three-dimensional, spectral or other information into peculiar Point-Spread Function (PSF) patterns. This concept allows for encoding multidimensional or multimodal information into a single image plane and to extract this information by an appropriate spatio-temporal correlation analysis of emitter fluctuations. Here, we develop the general theory of this concept, and present proof-of-principle experiments of three-dimensional super-resolution imaging. Copyright (C) EPLA, 2019
引用
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页数:6
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