Genesis, genes and epigenetics of endometriosis-associated infertility

被引：15

作者：

Guo, Sun-Wei ^{[1
,2
]}

机构：

[1] Fudan Univ, Shanghai Obstet & Gynecol Hosp, Shanghai, Peoples R China

[2] Shanghai Key Lab Female Reprod Endocrine Related, Shanghai, Peoples R China

来源：

NATURE REVIEWS ENDOCRINOLOGY | 2019年 / 15卷 / 05期

基金：

美国国家科学基金会;

关键词：

EXPRESSION; HOXA10;

D O I：

10.1038/s41574-019-0191-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Jae-Wook Jeong and colleagues report that histone deacetylase 3 (HDAC3) is downregulated in the endometrium of women with endometriosis. In addition, they show that the loss of HDAC3 is associated with aberrant hormonal signalling and increased fibrosis in the endometrium and impaired endometrial receptivity.

引用

页码：259 / 260

页数：2

共 10 条

[1] Fibrogenesis resulting from cyclic bleeding: the Holy Grail of the natural history of ectopic endometrium [J].

Guo, Sun-Wei .

HUMAN REPRODUCTION, 2018, 33 (03) :353-356

[2] Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions [J].

Hoeksema, Marten A. ;

Gijbels, Marion J. J. ;

Van den Bossche, Jan ;

van der Velden, Saskia ;

Sijm, Ayestha ;

Neele, Annette E. ;

Seijkens, Tom ;

Stoger, J. Lauran ;

Meiler, Svenja ;

Boshuizen, Marieke C. S. ;

Dallinga-Thie, Geesje M. ;

Levels, Johannes H. M. ;

Boon, Louis ;

Mullican, Shannon E. ;

Spann, Nathanael J. ;

Cleutjens, Jack P. ;

Glass, Chris K. ;

Lazar, Mitchell A. ;

de Vries, Carlie J. M. ;

Biessen, Erik A. L. ;

Daemen, Mat J. A. P. ;

Lutgens, Esther ;

de Winther, Menno P. J. .

EMBO MOLECULAR MEDICINE, 2014, 6 (09) :1124-1132

[3] Altered expression of HOXA10 in endometriosis: potential role in decidualization [J].

Kim, J. Julie ;

Taylor, H. S. ;

Lu, Z. ;

Ladhani, O. ;

Hastings, J. M. ;

Jackson, K. S. ;

Wu, Y. ;

Guo, S. W. ;

Fazleabas, A. T. .

MOLECULAR HUMAN REPRODUCTION, 2007, 13 (5-6) :323-332

[4] Loss of HDAC3 results in nonreceptive endometrium and female infertility [J].

Kim, Tae Hoon ;

Yoo, Jung-Yoon ;

Choi, Kyung-Chul ;

Shin, Jung-Ho ;

Leach, Richard E. ;

Fazleabas, Asgerally T. ;

Young, Steven L. ;

Lessey, Bruce A. ;

Yoon, Ho-Geun ;

Jeong, Jae-Wook .

SCIENCE TRANSLATIONAL MEDICINE, 2019, 11 (474)

[5] Transvaginal Elastosonography as an Imaging Technique for Diagnosing Adenomyosis [J].

Liu, Xishi ;

Ding, Ding ;

Ren, Yunyun ;

Guo, Sun-Wei .

REPRODUCTIVE SCIENCES, 2018, 25 (04) :498-514

[6] A Role for Estrogen Receptor-α and Estrogen Receptor-β in Collagen Biosynthesis in Mouse Skin [J].

Markiewicz, Margaret ;

Znoyko, Sergey ;

Stawski, Lukasz ;

Ghatnekar, Angela ;

Gilkeson, Gary ;

Trojanowska, Maria .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2013, 133 (01) :120-127

[7] HDAC3 regulates stability of estrogen receptor α mRNA [J].

Oie, Shohei ;

Matsuzaki, Kazuya ;

Yokoyama, Wataru ;

Murayama, Akiko ;

Yanagisawa, Junn .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 432 (02) :236-241

[8] HOX gene expression is altered in the endometrium of women with endometriosis [J].

Taylor, HS ;

Bagot, C ;

Kardana, A ;

Olive, D ;

Arici, A .

HUMAN REPRODUCTION, 1999, 14 (05) :1328-1331

[9] Is endometriosis an endometrial disease? [J].

Vinatier, D ;

Cosson, M ;

Dufour, P .

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2000, 91 (02) :113-125

[10] Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis [J].

Wu, Y ;

Halverson, G ;

Basir, Z ;

Strawn, E ;

Yan, P ;

Guo, SW .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2005, 193 (02) :371-380

← 1 →