Periodic Mesoporous Organosilica-Based Nanocomposite Hydrogels as Three-Dimensional Scaffolds

被引：67

作者：

Kehr, Nermin Seda ^{[1
,2
]}

Prasetyanto, Eko Adi ^{[1
,2
]}

Benson, Kathrin ^{[3
]}

Erguen, Bahar ^{[4
]}

Galstyan, Anzhela ^{[1
,2
]}

Galla, Hans-Joachim ^{[3
]}

机构：

[1] Univ Munster, Inst Phys, Heisenbergstr 11, D-48149 Munster, Germany

[2] Univ Munster, Ctr Nanotechnol, D-48149 Munster, Germany

[3] Univ Munster, Inst Biochem, D-48149 Munster, Germany

[4] Hacettepe Univ, Dept Chem, Div Biochem, TR-06800 Ankara, Turkey

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 04期

关键词：

cell adhesion; nanocomposite hydrogels; nanocontainers; mesoporous organosilica; three-dimensional scaffolds; ORGANIC GROUPS; CELL-ADHESION; BEHAVIOR; MORPHOLOGIES; FIBRONECTIN; SILICA; CLAY; GEL;

D O I：

10.1002/anie.201206951

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dye-loaded periodic mesoporous organosilica particles functionalized with bioactive molecules were used for the generation of a nanocomposite alginate hydrogel. The affinity of cells was up to four times higher with the embedded particles than with simple alginate hydrogel, caused by both the nanometer-scale particle itself and its bioactive functionalization. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1156 / 1160

页数：5

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