Periodic Mesoporous Organosilica-Based Nanocomposite Hydrogels as Three-Dimensional Scaffolds

被引:67
作者
Kehr, Nermin Seda [1 ,2 ]
Prasetyanto, Eko Adi [1 ,2 ]
Benson, Kathrin [3 ]
Erguen, Bahar [4 ]
Galstyan, Anzhela [1 ,2 ]
Galla, Hans-Joachim [3 ]
机构
[1] Univ Munster, Inst Phys, Heisenbergstr 11, D-48149 Munster, Germany
[2] Univ Munster, Ctr Nanotechnol, D-48149 Munster, Germany
[3] Univ Munster, Inst Biochem, D-48149 Munster, Germany
[4] Hacettepe Univ, Dept Chem, Div Biochem, TR-06800 Ankara, Turkey
关键词
cell adhesion; nanocomposite hydrogels; nanocontainers; mesoporous organosilica; three-dimensional scaffolds; ORGANIC GROUPS; CELL-ADHESION; BEHAVIOR; MORPHOLOGIES; FIBRONECTIN; SILICA; CLAY; GEL;
D O I
10.1002/anie.201206951
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Dye-loaded periodic mesoporous organosilica particles functionalized with bioactive molecules were used for the generation of a nanocomposite alginate hydrogel. The affinity of cells was up to four times higher with the embedded particles than with simple alginate hydrogel, caused by both the nanometer-scale particle itself and its bioactive functionalization. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:1156 / 1160
页数:5
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