LIVER FIBROSIS IN 2012 Convergent pathways that cause hepatic fibrosis in NASH

被引：54

作者：

Friedman, Scott L. ^{[1
]}

机构：

[1] Mt Sinai Sch Med, New York, NY 10029 USA

来源：

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2013年 / 10卷 / 02期

关键词：

DISEASE;

D O I：

10.1038/nrgastro.2012.256

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Efforts to understand fatty liver disease have focused on the gut microbiome's stimulation of hepatic injury and fibrosis through specialized signalling complexes at the cell surface and in the cytosol of liver cells. Combined with increased hedgehog activity and progenitor cell expansion, new clues are emerging to elucidate the pathogenesis of fibrosis. Friedman, S. L. Nat. Rev. Gastroenterol. Hepatol. 10, 71-72 (2013); published online 8 January 2013; doi:10.1038/nrgastro.2012.256

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页码：71 / 72

页数：2

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