Synthesis and anti-inflammatory evaluation of new sulfamoylheterocarboxylic derivatives

被引:5
|
作者
Diaz, JA
Morante, ME
Vega, S
Darias, V
Abdala, S
Delgado, L
Heras, BD
Villar, A
Vivas, JM
机构
[1] CSIC,INST QUIM MED,E-28006 MADRID,SPAIN
[2] UNIV LA LAGUNA,FAC FARM,DEPT FARMACOL,TENERIFE,SPAIN
[3] UNIV COMPLUTENSE MADRID,FAC FARM,DEPT FARMACOL,MADRID,SPAIN
关键词
sulfamoylthiophene and sulfamoylpyrazole carboxylic derivatives; analgesic activity; anti-inflammatory activity;
D O I
10.1002/ardp.19963290503
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A series of new sulfamoylthiophene and sulfamoylpyrazole carboxylic acid derivatives was synthesized. Some of these compounds show interesting analgesic properties and significant nonsteroidal anti-inflammatory activities in several models of inflammation.
引用
收藏
页码:229 / 238
页数:10
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