Atmospheric solids analysis probe: a rapid ionization technique for small molecule drugs

被引:58
作者
Petucci, Chris [1 ]
Diffendal, Jason [2 ]
机构
[1] Wyeth Ayerst Res, Discovery Analyt Chem, Collegeville, PA 19426 USA
[2] Wyeth Ayerst Res, Med Chem, Collegeville, PA 19426 USA
来源
JOURNAL OF MASS SPECTROMETRY | 2008年 / 43卷 / 11期
关键词
D O I
10.1002/jms.1424
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:1565 / 1568
页数:4
相关论文
共 16 条
[1]   Combining desorption electrospray ionization mass spectrometry and nuclear magnetic resonance for differential metabolomics without sample preparation [J].
Chen, Huanwen ;
Pan, Zhengzheng ;
Talaty, Nari ;
Raftery, Daniel ;
Cooks, R. Graham .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2006, 20 (10) :1577-1584
[2]   Versatile new ion source for the analysis of materials in open air under ambient conditions [J].
Cody, RB ;
Laramée, JA ;
Durst, HD .
ANALYTICAL CHEMISTRY, 2005, 77 (08) :2297-2302
[3]   COMPARISON OF POSITIVE-IONS FORMED IN NICKEL-63 AND CORONA DISCHARGE ION SOURCES USING NITROGEN, ARGON, ISOBUTANE, AMMONIA AND NITRIC-OXIDE AS REAGENTS IN ATMOSPHERIC-PRESSURE IONIZATION MASS-SPECTROMETRY [J].
DZIDIC, I ;
CARROLL, DI ;
STILLWELL, RN ;
HORNING, EC .
ANALYTICAL CHEMISTRY, 1976, 48 (12) :1763-1768
[4]   Direct mass spectrometric analysis of flavors and fragrances in real applications using DART [J].
Haefliger, Olivier P. ;
Jeckelmann, Nicolas .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2007, 21 (08) :1361-1366
[5]   Occurrence of radical molecular ions in atmospheric pressure chemical ionization mass spectra of heterocyclic compounds [J].
Holcapek, Michal ;
Lisa, Miroslav ;
Volna, Katerin ;
Almonasy, Numan ;
Prikryl, Josef .
JOURNAL OF MASS SPECTROMETRY, 2007, 42 (12) :1645-1648
[6]   Desorption electrospray ionization using an Orbitrap mass spectrometer: exact mass measurements on drugs and peptides [J].
Hu, Qizhi ;
Talaty, Nari ;
Noll, Robert J. ;
Cooks, R. Graham .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2006, 20 (22) :3403-3408
[7]   Desorption electrospray ionisation mass spectrometry and tandem mass spectrometry of low molecular weight synthetic polymers [J].
Jackson, Anthony T. ;
Williams, Jonathan P. ;
Scrivens, James H. .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2006, 20 (18) :2717-2727
[8]   Desorption electrospray ionization mass spectrometry for the analysis of pharmaceuticals and metabolites [J].
Kauppila, TJ ;
Wiseman, JM ;
Ketola, RA ;
Kotiaho, T ;
Cooks, RG ;
Kostiainen, R .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2006, 20 (03) :387-392
[9]   Analysis of the inhibition of the ergosterol pathway in fungi using the atmospheric solids analysis probe (ASAP) method [J].
McEwen, Charles ;
Gutteridge, Steven .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2007, 18 (07) :1274-1278
[10]   A combination atmospheric pressure LC/MS:GC/MS ion source:: Advantages of dual AP-LC/MS:GC/MS instrumentation [J].
McEwen, CN ;
McKay, RG .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2005, 16 (11) :1730-1738