Assembly of the type III secretion needle complex of Salmonella typhimurium

被引：76
作者：
Kimbrough, TG
Miller, SI
机构：
[1] Univ Washington, Dept Microbiol & Med, Seattle, WA 98195 USA
[2] Univ Washington, Dept Mol & Cellular Biol, Seattle, WA 98195 USA
来源：
MICROBES AND INFECTION | 2002年 / 4卷 / 01期
关键词：
Salmonella; type III secretion; needle complex;
D O I：
10.1016/S1286-4579(01)01512-X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The type III secretion needle complex (NC) of Salmonella typhimurium is a complex secretory system that functions to translocate virulence proteins into eukaryotic cells. Evolutionarily it is related to bacterial flagella. Assembly of the NC occurs through ordered secretion, polymerization, and assembly, and requires the coordinated expression and association of over 20 different proteins. Recent progress in the understanding of the assembly and architecture of the NC is reviewed. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
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页码：75 / 82
页数：8
相关论文
共 29 条
[1]   MXIJ, A LIPOPROTEIN INVOLVED IN SECRETION OF SHIGELLA IPA INVASINS, IS HOMOLOGOUS TO YSCJ, A SECRETION FACTOR OF THE YERSINIA YOP PROTEINS [J].
ALLAOUI, A ;
SANSONETTI, PJ ;
PARSOT, C .
JOURNAL OF BACTERIOLOGY, 1992, 174 (23) :7661-7669
[2]   Structure and composition of the Shigella flexneri 'needle complex', a part of its type III secreton [J].
Blocker, A ;
Jouihri, N ;
Larquet, E ;
Gounon, P ;
Ebel, F ;
Parsot, C ;
Sansonetti, P ;
Allaoui, A .
MOLECULAR MICROBIOLOGY, 2001, 39 (03) :652-663
[3]   The invasion-associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell [J].
Collazo, CM ;
Galan, JE .
MOLECULAR MICROBIOLOGY, 1997, 24 (04) :747-756
[4]   Salmonella InvG forms a ring-like multimer that requires the InvH lipoprotein for outer membrane localization [J].
Crago, AM ;
Koronakis, V .
MOLECULAR MICROBIOLOGY, 1998, 30 (01) :47-56
[5]   The Salmonella typhimurium InvH protein is an outer membrane lipoprotein required for the proper localization of InvG [J].
Daefler, S ;
Russel, M .
MOLECULAR MICROBIOLOGY, 1998, 28 (06) :1367-1380
[6]   MOLECULAR AND FUNCTIONAL-CHARACTERIZATION OF THE SALMONELLA-TYPHIMURIUM INVASION GENES INVB AND INVC - HOMOLOGY OF INVC TO THE F0F1 ATPASE FAMILY OF PROTEINS [J].
EICHELBERG, K ;
GINOCCHIO, CC ;
GALAN, JE .
JOURNAL OF BACTERIOLOGY, 1994, 176 (15) :4501-4510
[7]   The FliP and FliR proteins of Salmonella typhimurium, putative components of the type III flagellar export apparatus, are located in the flagellar basal body [J].
Fan, F ;
Ohnishi, K ;
Francis, NR ;
Macnab, RM .
MOLECULAR MICROBIOLOGY, 1997, 26 (05) :1035-1046
[8]   Type III secretion machines:: Bacterial devices for protein delivery into host cells [J].
Galán, JE ;
Collmer, A .
SCIENCE, 1999, 284 (5418) :1322-1328
[9]   CLONING AND MOLECULAR CHARACTERIZATION OF GENES WHOSE PRODUCTS ALLOW SALMONELLA-TYPHIMURIUM TO PENETRATE TISSUE-CULTURE CELLS [J].
GALAN, JE ;
CURTISS, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (16) :6383-6387
[10]   Genetic dissection of the outer membrane secretin PulD: Are there distinct domains for multimerization and secretion specificity? [J].
Guilvout, I ;
Hardie, KR ;
Sauvonnet, N ;
Pugsley, AP .
JOURNAL OF BACTERIOLOGY, 1999, 181 (23) :7212-7220
123