Preparation of Janus Droplets and Hydrogels with Controllable Morphologies by an Aqueous Two-Phase System on the Superamphiphobic Surface

被引:5
作者
Cheng, Quanyong [1 ]
Chen, Jingyi [1 ]
Wan, Chuchu [1 ]
Song, Yuhang [1 ]
Huang, Caili [1 ]
机构
[1] Huazhong Univ Sci & Technol HUST, Sch Chem & Chem Engn, Key Lab Mat Chem Energy Convers & Storage, Minist Educ, Wuhan 430074, Peoples R China
基金
中国国家自然科学基金;
关键词
Janus structure; aqueous two-phase systems; tunable morphology; organic solvent free; liquid-liquid phase separation; INDUCED PHASE-SEPARATION; NANOPARTICLES; EVAPORATION; COMBINATION; PARTITION; PARTICLES; EMULSIONS; PROTEINS; CELLS;
D O I
10.1021/acsami.2c16704
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Janus particles, having the property integration of each component, have attracted increasing attention due to their considerable potential in the field of material engineering applications. However, organic solvents or sophisticated equip-ment during the fabrication processes is generally inevitable. Here, we report a facile route to prepare Janus droplets and hydrogels via aqueous two-phase systems (ATPS). Simply merging two polymers, i.e., polyethylene glycol (PEG) and dextran (DEX), aqueous droplets on a superamphiphobic surface leads to phase separation, provided that their concentrations exceed the threshold in the mixed aqueous droplets, thus generating a Janus structure. Various morphologies of such Janus droplets can be well controlled by manipulating the locations of these two polymers' concentration on the phase diagram, and the evolution of the mixed droplets are deterministic on the basis of the kinetics of their phase separation and the degree of hydrophobicity of the substrate. Introducing monomers and/or nanoparticles, further, into a certain phase of the ATPS droplet followed by photopolymerizing enables Janus hydrogel particles with diverse functionalities to be obtained. The ease and green techniques with which the Janus balance and curvature between two phases of the Janus droplet can be finely tuned point to new directions in designing Janus particles and hold great promises in biological engineering.
引用
收藏
页码:50434 / 50443
页数:10
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