A novel type of receptor cDNA from the prothoracic glands of the silkworm, Bombyx mori

被引：5

作者：

Nagata, S

Namiki, T

Ko, R

Kataoka, H ^{[1
]}

Suzuki, A

机构：

[1] Univ Tokyo, Grad Sch Frontier Sci, Dept Integrated Biosci, Chiba 2778562, Japan

[2] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Tokyo 1138657, Japan

[3] Akita Prefectural Univ, Akita 0100195, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2006年 / 70卷 / 02期

基金：

日本学术振兴会;

关键词：

Bombyx mori; heptahelical receptor; molecular cloning; prothoracic glands; prothoracicotropic hormone (PTTH) receptor;

D O I：

10.1271/bbb.70.554

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cDNA encoding a novel heptahelical receptor from the prothoracic glands of the silkworm, Bombyx mori was cloned and sequenced during screening of a prothoracicotropic hormone (PTTH) receptor. Orthologs of this receptor are found not only in insects, but also in the vertebrates. In B. mori, ubiquitous expression of the mRNA was observed in the larva. Also, a higher expression level in the prothoracic glands was observed before molting and metamorphosis and was impaired after pupal molting. But, further analysis is required to confirm whether this receptor cDNA encodes the PTTH receptor.

引用

页码：554 / 558

页数：5

共 9 条

[1] Dynamic regulation of prothoracic gland ecdysteroidogenesis:: Manduca sexta recombinant prothoracicotropic hormone and brain extracts have identical effects [J].