Case 32-2020: A 63-Year-Old Man with Confusion, Fatigue, and Garbled Speech

被引:9
作者
Mukerji, Shibani S. [1 ,5 ]
Ard, Kevin L. [2 ,6 ]
Schaefer, Pamela W. [3 ,7 ]
Branda, John A. [4 ,8 ]
机构
[1] Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, Dept Radiol, Boston, MA USA
[4] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA
[5] Harvard Med Sch, Dept Neurol, Boston, MA 02115 USA
[6] Harvard Med Sch, Dept Med, Boston, MA 02115 USA
[7] Harvard Med Sch, Dept Radiol, Boston, MA 02115 USA
[8] Harvard Med Sch, Dept Pathol, Boston, MA 02115 USA
关键词
SPIROCHETE BORRELIA-MIYAMOTOI; UNITED-STATES; MENINGOENCEPHALITIS; ENCEPHALITIS; DISEASE;
D O I
10.1056/NEJMcpc2004996
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 63-year-old man with a history of primary membranous nephropathy presented with fever, confusion, headache, garbled speech, vision changes, lymphocytic pleocytosis, and an elevated CSF protein level. MRI of the head revealed sulcal hyperintensity on FLAIR images, with associated subtle enhancement on T1-weighted images. A diagnosis was made.
引用
收藏
页码:1578 / 1586
页数:9
相关论文
共 17 条
[1]   Investigation-Directed Approach to Inflammatory Optic Neuropathies [J].
Boudreault, Katherine ;
Durand, Marlene L. ;
Rizzo, Joseph F., III .
SEMINARS IN OPHTHALMOLOGY, 2016, 31 (1-2) :117-130
[2]   CNS Vasculitis: an Approach to Differential Diagnosis and Management [J].
Byram, Kevin ;
Hajj-Ali, Rula A. ;
Calabrese, Leonard .
CURRENT RHEUMATOLOGY REPORTS, 2018, 20 (07)
[3]   GENETIC AND PHENOTYPIC ANALYSIS OF BORRELIA-MIYAMOTOI SP-NOV, ISOLATED FROM THE IXODID TICK IXODES-PERSULCATUS, THE VECTOR FOR LYME-DISEASE IN JAPAN [J].
FUKUNAGA, M ;
TAKAHASHI, Y ;
TSURUTA, Y ;
MATSUSHITA, O ;
RALPH, D ;
MCCLELLAND, M ;
NAKAO, M .
INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 1995, 45 (04) :804-810
[4]   In search of encephalitis etiologies: Diagnostic challenges in the California Encephalitis Project, 1998-2000 [J].
Glaser, CA ;
Gilliam, S ;
Schnurr, D ;
Forghani, B ;
Honarmand, S ;
Khetsuriani, N ;
Fischer, M ;
Cossen, CK ;
Anderson, LJ .
CLINICAL INFECTIOUS DISEASES, 2003, 36 (06) :731-742
[5]   Meningoencephalitis from Borrelia miyamotoi in an Immunocompromised Patient [J].
Gugliotta, Joseph L. ;
Goethert, Heidi K. ;
Berardi, Victor P. ;
Telford, Sam R., III .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (03) :240-245
[6]   A case of meningoencephalitis by the relapsing fever spirochaete Borrelia miyamotoi in Europe [J].
Hovius, Joppe W. R. ;
de Wever, Bob ;
Sohne, Maaike ;
Brouwer, Matthijs C. ;
Coumou, Jeroen ;
Wagemakers, Alex ;
Oei, Anneke ;
Knol, Henrike ;
Narasimhan, Sukanya ;
Hodiamont, Caspar J. ;
Jahfari, Setareh ;
Pals, Steven T. ;
Horlings, Hugo M. ;
Fikrig, Erol ;
Sprong, Hein ;
van Oers, Marinus H. J. .
LANCET, 2013, 382 (9892) :658-658
[7]   Serodiagnosis of Borrelia miyamotoi disease by measuring antibodies against GlpQ and variable major proteins [J].
Koetsveld, J. ;
Kolyasnikova, N. M. ;
Wagemakers, A. ;
Stukolova, O. A. ;
Hoornstra, D. ;
Sarksyan, D. S. ;
Toporkova, M. G. ;
Henningsson, A. J. ;
Hvidsten, D. ;
Ang, W. ;
Dessau, R. ;
Platonov, A. E. ;
Hovius, J. W. .
CLINICAL MICROBIOLOGY AND INFECTION, 2018, 24 (12) :1338.e1-1338.e7
[8]  
Koetsveld J, 2017, ANTIMICROB AGENTS CH, V61, DOI [10.1128/AAC.00535-17, 10.1128/aac.00535-17]
[9]   Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study [J].
McGill, Fiona ;
Griffiths, Michael J. ;
Bonnett, Laura J. ;
Geretti, Anna Maria ;
Michael, Benedict D. ;
Beeching, Nicholas J. ;
McKee, David ;
Scarlett, Paula ;
Hart, Ian J. ;
Mutton, Kenneth J. ;
Jung, Agam ;
Adan, Guleed ;
Gummery, Alison ;
Sulaiman, Wan Aliaa Wan ;
Ennis, Katherine ;
Martin, Antony P. ;
Haycox, Alan ;
Miller, Alastair ;
Solomon, Tom .
LANCET INFECTIOUS DISEASES, 2018, 18 (09) :992-1003
[10]   Borrelia miyamotoi Disease in the Northeastern United States A Case Series [J].
Molloy, Philip J. ;
Telford, Sam R., III ;
Chowdri, Hanumara Ram ;
Lepore, Timothy J. ;
Gugliotta, Joseph L. ;
Weeks, Karen E. ;
Hewins, Mary Ellen ;
Goethert, Heidi K. ;
Berardi, Victor P. .
ANNALS OF INTERNAL MEDICINE, 2015, 163 (02) :91-+