The failing heart

被引：361

作者：

Towbin, JA ^{[1
]}

Bowles, NE

机构：

[1] Baylor Coll Med, Dept Pediat Cardiol, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA

[3] Baylor Coll Med, Dept Cardiovasc Sci, Houston, TX 77030 USA

来源：

NATURE | 2002年 / 415卷 / 6868期

关键词：

D O I：

10.1038/415227a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cardiomyopathies are disorders affecting heart muscle that usually result in inadequate pumping of the heart. They are the most common cause of heart failure and each year kill more than 10,000 people in the United States. In recent years, there have been breakthroughs in understanding the molecular mechanisms involved in this group of conditions, with knowledge of the genetic basis for cardiomyopathies perhaps seeing the largest advance, enabling clinicians to devise improved diagnostic strategies and preparing the stage for new therapies.

引用

页码：227 / 233

页数：7

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