Formation of tryptanthrin compounds upon Oxone-induced dimerization of indole-3-carbaldehydes

被引：31

作者：

Nelson, Amber C. ^{[1
]}

Kalinowski, Emily S. ^{[1
]}

Jacobson, Taylor L. ^{[1
]}

Grundt, Peter ^{[1
]}

机构：

[1] Univ Minnesota, Dept Chem & Biochem, Duluth, MN 55812 USA

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 50期

关键词：

Natural product synthesis; Tryptanthrin; Oxidation; TOXOPLASMA-GONDII; ANTHRANILIC ACIDS; DERIVATIVES; OXIDATION; INDOLES; PHARMACOPHORE; INHIBITION; CHEMISTRY; ANALOGS;

D O I：

10.1016/j.tetlet.2013.09.124

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tryptanthrin is a natural product with numerous important pharmacological properties. Tryptanthrin and its analogs are commonly prepared by condensation of isatoic anhydride and isatin. In this Letter we investigate the formation of tryptanthrin derivatives upon Oxone-induced oxidative dimerization of indole-3-carbaldehydes. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：6804 / 6806

页数：3

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