An efficient method for the synthesis of 1,5-benzodiazepine derivatives under microwave irradiation without solvent

被引：163

作者：

Pozarentzi, M ^{[1
]}

Stephanidou-Stephanatou, J ^{[1
]}

Tsoleridis, CA ^{[1
]}

机构：

[1] Aristotle Univ Thessaloniki, Dept Chem, Organ Chem Lab, GR-54006 Thessaloniki, Macedonia, Greece

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 09期

关键词：

benzodiazepines; o-phenylenediamines; microwave irradiation; green chemistry;

D O I：

10.1016/S0040-4039(02)00115-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2, 3-Dihydro-1H-1.5-benzodiazepines have been synthesized in solvent-free conditions from o-phenylenediamines and ketones in the presence of a catalytic amount of acetic acid, under microwave irradiation. This method is a very easy, rapid and high yielding reaction for the synthesis of 1,5-benzodiazepine derivatives. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1755 / 1758

页数：4

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[21] INVITED REVIEW - DEVELOPMENTS IN MICROWAVE-ASSISTED ORGANIC-CHEMISTRY [J].