An efficient method for the synthesis of 1,5-benzodiazepine derivatives under microwave irradiation without solvent

被引：160
作者：
Pozarentzi, M [1 ]
Stephanidou-Stephanatou, J [1 ]
Tsoleridis, CA [1 ]
机构：
[1] Aristotle Univ Thessaloniki, Dept Chem, Organ Chem Lab, GR-54006 Thessaloniki, Macedonia, Greece
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 09期
关键词：
benzodiazepines; o-phenylenediamines; microwave irradiation; green chemistry;
D O I：
10.1016/S0040-4039(02)00115-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
2, 3-Dihydro-1H-1.5-benzodiazepines have been synthesized in solvent-free conditions from o-phenylenediamines and ketones in the presence of a catalytic amount of acetic acid, under microwave irradiation. This method is a very easy, rapid and high yielding reaction for the synthesis of 1,5-benzodiazepine derivatives. (C) 2002 Elsevier Science Ltd. All rights reserved.
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收藏
页码：1755 / 1758
页数：4
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