Mineralisation of Developmentally Hypomineralised Human Enamel in vitro

被引：28

作者：

Crombie, F. A. ^{[1
]}

Cochrane, N. J. ^{[1
]}

Manton, D. J. ^{[1
]}

Palamara, J. E. A. ^{[1
]}

Reynolds, E. C. ^{[1
]}

机构：

[1] Univ Melbourne, Melbourne Dent Sch, Oral Hlth Cooperat Res Ctr, Parkville, Vic 3052, Australia

来源：

CARIES RESEARCH | 2013年 / 47卷 / 03期

关键词：

Casein phosphopeptide amorphous calcium fluoride phosphate; Developmental enamel defects; Mineralisation; Molar-incisor hypomineralisation; MOLAR INCISOR HYPOMINERALIZATION; HUMAN CARIES LESIONS; DENTAL ENAMEL; REMINERALIZATION; PHOSPHATE; FLUORIDE; INVITRO; CALCIUM;

D O I：

10.1159/000346134

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Molar-incisor hypomineralisation (MIH) is a problematic and costly condition. Caries remineralising agents are often recommended for MIH management despite the lack of evidence that these lesions have the capacity for increasing their mineral content. Following surface layer removal +/- NaOCl pre-treatment and 14-day exposure to a CPP-ACFP solution at pH 5.5, MIH lesions were analysed using transverse microradiography and polarised light microscopy. Lesions were highly variable but treatment with the remineralising solution increased mineral content (1,828 +/- 461 vol% min . mu m, %R = 17.7 +/- 5.7) and porosity decreased demonstrating the proof of concept that the mineral content of developmentally hyponnineralised enamel can be improved after eruption. Copyright (C) 2013 S. Karger AG, Basel

引用

页码：259 / 263

页数：5

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