Near Missed Case of Occupational Pleural Malignant Mesothelioma, a Case Report and Latest Therapeutic Options

被引:5
作者
Handra, Claudia-Mariana [1 ]
Chirila, Marinela [2 ]
Smarandescu, Raluca-Andreea [1 ]
Ghita, Isabel [3 ]
机构
[1] Carol Davila Univ Med & Pharm, Occupat Hlth Dept, Bucharest 050474, Romania
[2] Titu Maiorescu Univ, Fac Pharm, Bucharest 040441, Romania
[3] Carol Davila Univ Med & Pharm, Pharm & Pharmacol Dept, Bucharest 050474, Romania
关键词
pleural malignant mesothelioma; asbestos; occupational exposure; DIAGNOSIS; EPIDEMIOLOGY;
D O I
10.3390/ijerph192214763
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Asbestos use started to be gradually banned in Europe from 1991 onwards, and there are currently strict occupational exposure limits for asbestos. However, malignant mesothelioma has a long latency time (in some cases up to 50-60 years), so the risks related to asbestos exposure should not be forgotten. Considering the increased risk of lung cancer following the inhalation of asbestos fibers, lifetime health monitoring should be considered in people occupationally exposed to asbestos, with an emphasis on the respiratory system. An assessment of their occupational history should be performed rigorously, especially in the areas with a history of asbestos production/use, as this is a key element for an early diagnosis and appropriate treatment. This case report presents a near-missed case of occupational pleural malignant mesothelioma. The latency time between the first asbestos exposure and the diagnosis of occupational pleural malignant mesothelioma was 49 years. The accurate diagnosis was made two years after the first symptoms appeared.
引用
收藏
页数:8
相关论文
共 25 条
[1]   The pathological and molecular diagnosis of malignant pleural mesothelioma: a literature review [J].
Ali, Greta ;
Bruno, Rossella ;
Fontanini, Gabriella .
JOURNAL OF THORACIC DISEASE, 2018, 10 :S276-S284
[2]   Epidemiology of mesothelioma in the 21st century in Europe and the United States, 40 years after restricted/banned asbestos use [J].
Alpert, Naomi ;
van Gerwen, Maaike ;
Taioli, Emanuela .
TRANSLATIONAL LUNG CANCER RESEARCH, 2020, 9 :S28-S38
[3]  
[Anonymous], GHID SUPRAVEGHERE RI
[4]   Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment [J].
Bibby, Anna C. ;
Tsim, Selina ;
Kanellakis, Nikolaos ;
Ball, Hannah ;
Talbot, Denis C. ;
Blyth, Kevin G. ;
Maskell, Nick A. ;
Psallidas, Ioannis .
EUROPEAN RESPIRATORY REVIEW, 2016, 25 (142) :472-486
[5]   Epidemiology and Clinical Aspects of Malignant Pleural Mesothelioma [J].
Brims, Fraser .
CANCERS, 2021, 13 (16)
[6]   Global use of asbestos-legitimate and illegitimate issues [J].
Frank, Arthur L. .
JOURNAL OF OCCUPATIONAL MEDICINE AND TOXICOLOGY, 2020, 15 (01)
[7]   Phase I Study of Tremelimumab Monotherapy or in Combination With Durvalumab in Japanese Patients With Advanced Solid Tumors or Malignant Mesothelioma [J].
Fujiwara, Yutaka ;
Takahashi, Yasuo ;
Okada, Morihito ;
Kishimoto, Takumi ;
Kondo, Shunsuke ;
Fujikawa, Koshi ;
Hayama, Manabu ;
Sugeno, Masatoshi ;
Ueda, Shinya ;
Komuro, Keiko ;
Lanasa, Mark ;
Nakano, Takashi .
ONCOLOGIST, 2022, 27 (09) :E703-E722
[8]   Emerging avenues in immunotherapy for the management of malignant pleural mesothelioma [J].
Gray, Steven G. .
BMC PULMONARY MEDICINE, 2021, 21 (01)
[9]   Malignant mesothelioma of the pleura with desmoplastic histology: a case series and literature review [J].
Hashimoto, Kana ;
Okuma, Yusuke ;
Hosomi, Yukio ;
Hishima, Tsunekazu .
BMC CANCER, 2016, 16
[10]   Palliative surgical debulking in malignant mesothelioma - Predictors of survival and symptom control [J].
Martin-Ucar, AE ;
Edwards, JG ;
Rengajaran, A ;
Muller, S ;
Waller, DA .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2001, 20 (06) :1117-1121