Inhibition of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis by diospyrin, isolated from Euclea natalensis

被引：49
作者：
Lall, N [1 ]
Meyer, JJM [1 ]
机构：
[1] Univ Pretoria, Dept Bot, ZA-0002 Pretoria, South Africa
来源：
JOURNAL OF ETHNOPHARMACOLOGY | 2001年 / 78卷 / 2-3期
基金：
英国医学研究理事会;
关键词：
diospyrin; Euclea natalensis; Mycobacterium tuberculosis;
D O I：
10.1016/S0378-8741(01)00356-7
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The binaphthoquinoid, diospyrin, was isolated from Euclea natalensis A.DC., and evaluated for its activity against drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis. The minimal inhibitory concentration (MIC) of diospyrin was found to be 100 mug/ml for all the M. tuberculosis strains. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：213 / 216
页数：4
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